Dernbach P D, Gomez H, Hahn J
Department of Neurosurgery, Lahey Clinic Medical Center, Cleveland, Ohio.
Neurosurgery. 1990 Apr;26(4):707-9. doi: 10.1097/00006123-199004000-00028.
Although postoperative infections of spinal wounds are uncommon, when they occur, they cause considerable morbidity. The classic treatment for deep infected wounds of the spine involves opening the wound, packing it, and permitting secondary closure to occur through granulation. A combined total of 10 patients with infected postoperative spinal wounds (two cervical and eight lumbar) from the Lahey Clinic and the Cleveland Clinic were treated by primary closure. Infection was diagnosed, usually within 2 weeks of operation (average, 10.9 days), by increasing back pain, purulent drainage from the incision, cultures, and subfacial extension of the process. In one patient, an associated disk space infection was observed. Causative organisms were Staphylococcus aureus in five patients and Staphylococcus epidermidis in five patients. At the second operation, the wounds were opened and radically debrided, irrigated, and closed primarily over one or two large drains. Treatment with intravenously administered antibiotics was continued postoperatively; the duration of treatment varied from 10 days to 6 weeks, depending on the presence or absence of involvement of bone or disks. Complete resolution of the infections and primary healing of the wounds occurred in all patients. This technique offers advantages over the traditional technique of secondary wound closure by decreasing the amount of wound care and length of hospitalization and is recommended as the treatment of choice for patients with postoperative spinal wound infections.
虽然脊柱伤口术后感染并不常见,但一旦发生,会导致相当高的发病率。脊柱深部感染伤口的经典治疗方法包括打开伤口、填塞,然后通过肉芽组织实现二期愈合。来自拉希诊所和克利夫兰诊所的总共10例脊柱术后伤口感染患者(2例颈椎,8例腰椎)接受了一期缝合治疗。感染通常在术后2周内(平均10.9天)通过背痛加剧、切口脓性引流、培养以及感染过程的皮下扩展来诊断。1例患者观察到合并椎间盘间隙感染。5例患者的病原体为金黄色葡萄球菌,5例为表皮葡萄球菌。在二次手术时,打开伤口,彻底清创、冲洗,然后在一两个大引流管上方进行一期缝合。术后继续静脉使用抗生素治疗;治疗持续时间从10天到6周不等,取决于是否累及骨骼或椎间盘。所有患者感染均完全消退,伤口一期愈合。该技术相对于传统的二期伤口闭合技术具有优势,可减少伤口护理量和住院时间,推荐作为脊柱术后伤口感染患者的首选治疗方法。