Li Yong-ping
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yan-Sen University, Guangzhou 510080, China.
Zhonghua Yan Ke Za Zhi. 2012 Nov;48(11):971-5.
Melanoma of the uveal tract is most common primary intraocular cancer in adults. Approximately 50% of patients with uveal melanoma died from metastasis, irrespective of the type of treatment. Enucleation was the primary form of treatment and the best option. Whether the enucleation of the eye containing uveal melanoma accelerates metastatic death has long been a controversial topic. The combination of pathological and some experimental studies in progress concerning this contentious topic is discussed in the current article.
葡萄膜黑色素瘤是成年人中最常见的原发性眼内癌。无论采用何种治疗方式，约50%的葡萄膜黑色素瘤患者死于转移。眼球摘除术曾是主要的治疗方式及最佳选择。摘除患有葡萄膜黑色素瘤的眼球是否会加速转移性死亡长期以来一直是个有争议的话题。本文讨论了关于这个有争议话题的病理学和一些正在进行的实验研究的结合情况。
