School of Pharmacy, Zhengzhou University, Zhengzhou 450001, China.
Chin J Nat Med. 2012 Jan;10(1):43-7. doi: 10.1016/S1875-5364(12)60010-7.
To study the chemical constituents in the flowers and fruits of Rabdosia excisa.
The compounds were isolated and purified by silica gel column chromatography and their structures were identified by spectroscopic methods.
Sixteen compounds isolated from the flowers and fruits of this plant were identified as: stigm asterol (I), α-amyrin palmitate (II), ursolic acid (III), 2α, 3α, 19-trihydroxy-urs-12-en-28-oic acid (IV), 2α-hydroxyursolic acid (V), maslinic acid (VI), isodonal (VII), maoyecrystal E (VIII), kamebakaurin (XI), macrocalyxin G (X), epinodosinol (XI), rabdosichuanin C (XII), kamebacetal A (XIII), oridonin (XIV), enmenol-glucoside (XV), and lasiononin (XVI).
All the constituents were found in Rabdosia excisa for the first time, except constituents III, IX, XII and XIV.
研究溪黄草花和果中的化学成分。
采用硅胶柱色谱分离纯化化合物,根据波谱数据鉴定其结构。
从溪黄草花和果中分离得到 16 个化合物,分别鉴定为:豆甾醇(I)、α-香树脂醇棕榈酸酯(II)、熊果酸(III)、2α,3α,19-三羟基乌苏-12-烯-28-酸(IV)、2α-羟基乌苏酸(V)、齐墩果酸(VI)、异土木香内酯(VII)、茅药醇 E(VIII)、卡马新(XI)、大根香叶素 G(X)、epinodosinol(XI)、岩黄连 C(XII)、卡马亭 A(XIII)、冬凌草甲素(XIV)、enmenol-葡萄糖苷(XV)和lasiononin(XVI)。
除化合物 III、IX、XII 和 XIV 外,其余化合物均首次从溪黄草中分离得到。