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Usefulness of immunocytochemistry for the detection of the BRAF(V600E) mutation in circulating tumor cells from metastatic melanoma patients.

作者信息

Hofman Véronique, Ilie Marius, Long-Mira Elodie, Giacchero Damien, Butori Catherine, Dadone Bérengère, Selva Eric, Tanga Virginie, Passeron Thierry, Poissonnet Gilles, Emile Jean-François, Lacour Jean-Philippe, Bahadoran Philippe, Hofman Paul

出版信息

J Invest Dermatol. 2013 May;133(5):1378-81. doi: 10.1038/jid.2012.485. Epub 2013 Jan 10.

DOI:10.1038/jid.2012.485
PMID:23303445
Abstract
摘要

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Accurate detection of BRAF p.V600E mutations in challenging melanoma specimens requires stringent immunohistochemistry scoring criteria or sensitive molecular assays.在具有挑战性的黑色素瘤标本中准确检测BRAF p.V600E突变需要严格的免疫组织化学评分标准或灵敏的分子检测方法。
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引用本文的文献

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Curr Treat Options Oncol. 2022 Apr;23(4):562-577. doi: 10.1007/s11864-022-00948-2. Epub 2022 Mar 17.
2
Predictive Evaluation on Cytological Sample of Metastatic Melanoma: The Role of BRAF Immunocytochemistry in the Molecular Era.转移性黑色素瘤细胞学样本的预测性评估：BRAF免疫细胞化学在分子时代的作用。
Diagnostics (Basel). 2021 Jun 18;11(6):1110. doi: 10.3390/diagnostics11061110.
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The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape.
BRAF 突变型黑色素瘤领域分子检测的现状
Front Mol Biosci. 2020 Jun 30;7:113. doi: 10.3389/fmolb.2020.00113. eCollection 2020.
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Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients.利用转移性黑色素瘤患者的游离循环肿瘤DNA监测BRAF和NRAS突变。
Oncotarget. 2018 Nov 16;9(90):36238-36249. doi: 10.18632/oncotarget.26343.
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Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.开发超短 PCR 检测法以揭示泰国结直肠癌组织中的 BRAF V600 突变状态。
PLoS One. 2018 Jun 7;13(6):e0198795. doi: 10.1371/journal.pone.0198795. eCollection 2018.
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Single-cell genetic analysis validates cytopathological identification of circulating cancer cells in patients with clear cell renal cell carcinoma.单细胞基因分析验证了透明细胞肾细胞癌患者循环癌细胞的细胞病理学鉴定。
Oncotarget. 2018 Apr 13;9(28):20058-20074. doi: 10.18632/oncotarget.25102.
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Liquid Biopsy and Therapeutic Targets: Present and Future Issues in Thoracic Oncology.液体活检与治疗靶点：胸部肿瘤学的现状与未来问题
Cancers (Basel). 2017 Nov 10;9(11):154. doi: 10.3390/cancers9110154.
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Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion.用于肿瘤侵袭早期检测的固定和活循环肿瘤细胞高灵敏度分离及分子特征分析的技术见解
PLoS One. 2017 Jan 6;12(1):e0169427. doi: 10.1371/journal.pone.0169427. eCollection 2017.
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