USDOE-Ames Laboratory, Ames, IA 50011, USA.
J Mass Spectrom. 2013 Jan;48(1):100-4. doi: 10.1002/jms.3134.
We have previously developed in-parallel data acquisition of orbitrap mass spectrometry (MS) and ion trap MS and/or MS/MS scans for matrix-assisted laser desorption/ionization MS imaging (MSI) to obtain rich chemical information in less data acquisition time. In the present study, we demonstrate a novel application of this multiplex MSI methodology for latent fingerprints. In a single imaging experiment, we could obtain chemical images of various endogenous and exogenous compounds, along with simultaneous MS/MS images of a few selected compounds. This work confirms the usefulness of multiplex MSI to explore chemical markers when the sample specimen is very limited.
我们之前已经开发了用于轨道阱质谱（MS）和离子阱 MS 和/或 MS/MS 扫描的并行数据采集，用于基质辅助激光解吸/电离 MS 成像（MSI），以在更短的数据采集时间内获得丰富的化学信息。在本研究中，我们展示了这种多路复用 MSI 方法在潜伏指纹中的新应用。在单个成像实验中，我们可以获得各种内源性和外源性化合物的化学图像，以及一些选定化合物的同时 MS/MS 图像。这项工作证实了在样本非常有限的情况下，多路复用 MSI 用于探索化学标志物的有用性。
