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Am J Med. 2011 Aug;124(8):698-701. doi: 10.1016/j.amjmed.2010.07.032. Epub 2011 Jun 12.
4
Vaccination against hepatitis B among prisoners in Iran: accelerated vs. classic vaccination.伊朗囚犯的乙型肝炎疫苗接种：加速与经典疫苗接种。
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5
[Study on the immunization coverage and effects of hepatitis B vaccine in the 20-59 years-old population in Guangzhou city].广州市20至59岁人群乙肝疫苗免疫接种率及效果研究
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7
Persistence of antibodies and immune memory to hepatitis B vaccine 20 years after infant vaccination in Thailand.泰国婴儿接种乙型肝炎疫苗 20 年后，乙型肝炎疫苗的抗体和免疫记忆持续存在。
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8
Chronic hepatitis B.慢性乙型肝炎
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9
A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults.在美国消除乙肝病毒感染传播的综合免疫策略：免疫实践咨询委员会（ACIP）的建议 第二部分：成人免疫接种
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[Coverage of vaccination against hepatitis B in Poland in 2004].[2004年波兰乙型肝炎疫苗接种情况]
Przegl Epidemiol. 2006;60(2):185-92.

针对婚前检查中被确定为乙肝携带者的配偶的快速免疫方案。

Rapid immunization scheme for spouses of individuals estabilished as hepatitis B carriers during premarital tests.

作者信息

Tosun Selma, Yücetürk Murat, Dönmez Aydın Bilal, Gündüz Turan

机构信息

Department of Clinical Microbiology and Infectious Diseases, Manisa State Hospital, Manisa, Turkey.

出版信息

Clin Dev Immunol. 2012;2012:843134. doi: 10.1155/2012/843134. Epub 2012 Dec 13.

DOI:10.1155/2012/843134
PMID:23304191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3530868/
Abstract

BACKGROUND

The aim of this study was to monitor the cases identified as hepatitis B carriers during premarital tests, to vaccinate their prospective spouses with a rapid vaccination scheme, and to compare the anti-HBs responses with the traditional vaccination scheme.

METHODS

Blood samples of 1250 couple spouses were tested for HBsAg and anti-HBs. HBsAg positive cases' fiancées which were found HBV negative were administered a rapid three-dose vaccination scheme on days 0, 7, and 21. Forty controls with similar age and gender were also were administered three doses of the same vaccine.

RESULTS

Out of 1250 cases (625 couples), 46 (3.6%) were HBsAg positive, and 40 of them aged between 18 and 39 were admitted to the rapid vaccination program.

CONCLUSION

Upon determination of HBsAg positivity in premarital tests, a rapid vaccination program provides early protection, but the 6th and 12th month vaccinations are also required. Anti-HBs response should be monitored.

摘要

背景

本研究的目的是监测婚前检查中被确定为乙肝携带者的病例，为其准配偶实施快速接种方案，并将抗-HBs反应与传统接种方案进行比较。

方法

对1250对配偶的血液样本进行HBsAg和抗-HBs检测。对HBsAg阳性病例中HBV阴性的未婚妻在第0、7和21天实施快速三剂接种方案。还对40名年龄和性别相似的对照者接种三剂相同疫苗。

结果

在1250例（625对）病例中，46例（3.6%）HBsAg呈阳性，其中40例年龄在18至39岁之间的被纳入快速接种计划。

结论

在婚前检查确定HBsAg阳性后，快速接种方案可提供早期保护，但仍需在第6个月和第12个月进行接种。应监测抗-HBs反应。