Lee Eva K, Yuan Fan, Hirsh Daniel A, Mallory Michael D, Simon Harold K
Center for Operations Research in Medicine and HealthCare, Georgia Institute of Technology, Georgia, USA.
AMIA Annu Symp Proc. 2012;2012:495-504. Epub 2012 Nov 3.
The primary purpose of this study was to develop a clinical tool capable of identifying discriminatory characteristics that can predict patients who will return within 72 hours to the Pediatric emergency department (PED). We studied 66,861 patients who were discharged from the EDs during the period from May 1 2009 to December 31 2009. We used a classification model to predict return visits based on factors extracted from patient demographic information, chief complaint, diagnosis, treatment, and hospital real-time ED statistics census. We began with a large pool of potentially important factors, and used particle swarm optimization techniques for feature selection coupled with an optimization-based discriminant analysis model (DAMIP) to identify a classification rule with relatively small subsets of discriminatory factors that can be used to predict - with 80% accuracy or greater - return within 72 hours. The analysis involves using a subset of the patient cohort for training and establishment of the predictive rule, and blind predicting the return of the remaining patients. Good candidate factors for revisit prediction are obtained where the accuracy of cross validation and blind prediction are over 80%. Among the predictive rules, the most frequent discriminatory factors identified include diagnosis (> 97%), patient complaint (>97%), and provider type (> 57%). There are significant differences in the readmission characteristics among different acuity levels. For Level 1 patients, critical readmission factors include patient complaint (>57%), time when the patient arrived until he/she got an ED bed (> 64%), and type/number of providers (>50%). For Level 4/5 patients, physician diagnosis (100%), patient complaint (99%), disposition type when patient arrives and leaves the ED (>30%), and if patient has lab test (>33%) appear to be significant. The model was demonstrated to be consistent and predictive across multiple PED sites.The resulting tool could enable ED staff and administrators to use patient specific values for each of a small number of discriminatory factors, and in return receive a prediction as to whether the patient will return to the ED within 72 hours. Our prediction accuracy can be as high as over 85%. This provides an opportunity for improving care and offering additional care or guidance to reduce ED readmission.
本研究的主要目的是开发一种临床工具,该工具能够识别出具有鉴别性的特征,从而预测哪些患者会在72小时内返回儿科急诊科(PED)。我们研究了2009年5月1日至2009年12月31日期间从急诊科出院的66861名患者。我们使用一种分类模型,基于从患者人口统计学信息、主诉、诊断、治疗以及医院急诊科实时统计普查中提取的因素来预测复诊情况。我们从大量潜在的重要因素入手,运用粒子群优化技术进行特征选择,并结合基于优化的判别分析模型(DAMIP),以识别出具有相对较少鉴别因素子集的分类规则,该规则可用于以80%或更高的准确率预测72小时内的复诊情况。分析过程包括使用患者队列的一个子集进行训练并建立预测规则,然后对其余患者进行盲态预测。当交叉验证和盲态预测的准确率超过80%时,可获得用于复诊预测的良好候选因素。在预测规则中,识别出的最常见鉴别因素包括诊断(>97%)、患者主诉(>97%)和医疗服务提供者类型(>57%)。不同急症程度患者的再入院特征存在显著差异。对于1级患者,关键的再入院因素包括患者主诉(>57%)、患者到达至获得急诊科床位的时间(>64%)以及医疗服务提供者的类型/数量(>50%)。对于4/5级患者,医生诊断(100%)、患者主诉(99%)、患者到达和离开急诊科时的处置类型(>30%)以及患者是否进行了实验室检查(>33%)似乎具有显著性。该模型在多个儿科急诊科站点均表现出一致性和预测性。由此产生的工具可使急诊科工作人员和管理人员针对少数鉴别因素使用患者的具体值,并据此获得患者是否会在72小时内返回急诊科的预测。我们的预测准确率可高达85%以上。这为改善护理以及提供额外护理或指导以减少急诊科再入院提供了机会。