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快速康复计划可显著缩短单纯胰十二指肠切除术后的住院时间。

A fast track recovery program significantly reduces hospital length of stay following uncomplicated pancreaticoduodenectomy.

作者信息

Nikfarjam Mehrdad, Weinberg Laurence, Low Nicholas, Fink Michael A, Muralidharan Vijayaragavan, Houli Nezor, Starkey Graham, Jones Robert, Christophi Christopher

机构信息

Department of Surgery, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.

出版信息

JOP. 2013 Jan 10;14(1):63-70. doi: 10.6092/1590-8577/1223.

Abstract

CONTEXT

Factors affecting length of hospital stay after uncomplicated pancreaticoduodenectomy have not been reported. We hypothesized that patients undergoing uncomplicated pancreaticoduodenectomy treated by fast track recovery program would have a shorter length of hospital stay compared to those managed by a standard program.

METHODS

Patients without surgical or medical complications following pancreaticoduodenectomy managed by fast track or standard protocols, between 2005 and 2011, were identified and prognostic predictors for length of hospital stay determined.

RESULTS

Forty-one patients treated by pancreaticoduodenectomy had no medical or surgical complications during this period. Of these patients, 20 underwent fast track recovery program compared to 21 who underwent standard care. Patients in the standard group were more likely to have a feeding jejunostomy tube (P<0.001), pylorus preserving procedure (P=0.001) and a nasogastric tube in place longer than 24 hours postoperatively (P<0.001). The median postoperative length of stay was shorter in the fast track recovery program group (8 days, range: 7-16 days) versus 14 days, range: 8-29 days; P<0.001). There were three readmissions in the fast track recovery program related to abdominal pain and none in the standard group. The overall length of stay, accounting for readmissions, still remained significantly shorter in the fast track recovery program group (median 9 days, range: 7-17 days versus median14 days, range: 8-29 days ; P<0.001). There were no significant differences in discharge destination between groups. On multivariate analysis, the only factor independently associated with postoperative discharge by day 8 was fast track recovery program (OR: 37.1, 95% CI: 4.08-338; P<0.001).

CONCLUSION

Fast track recovery program achieved significantly shorter length of stay following uncomplicated pancreaticoduodenectomy.

摘要

背景

目前尚无关于单纯胰十二指肠切除术后影响住院时间因素的报道。我们推测,与采用标准方案治疗的患者相比,接受快速康复计划治疗的单纯胰十二指肠切除术患者的住院时间会更短。

方法

确定2005年至2011年间采用快速康复或标准方案治疗且胰十二指肠切除术后无手术或医疗并发症的患者,并确定住院时间的预后预测因素。

结果

在此期间,41例行胰十二指肠切除术的患者无医疗或手术并发症。其中,20例接受快速康复计划,21例接受标准治疗。标准组患者更有可能留置空肠造瘘管(P<0.001)、行保留幽门手术(P=0.001)以及术后鼻胃管留置时间超过24小时(P<0.001)。快速康复计划组术后中位住院时间较短(8天,范围:7 - 16天),而标准组为14天(范围:8 - 29天);P<0.001)。快速康复计划组有3例因腹痛再次入院,标准组无再次入院情况。考虑再次入院因素后,快速康复计划组的总住院时间仍显著较短(中位9天,范围:7 - 17天,而标准组中位14天,范围:8 - 29天;P<0.001)。两组之间出院去向无显著差异。多因素分析显示,与术后第8天出院独立相关的唯一因素是快速康复计划(OR:37.1,95%CI:4.08 - 338;P<0.001)。

结论

快速康复计划显著缩短了单纯胰十二指肠切除术后的住院时间。

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