Malov Iu S
Vrach Delo. 1990 Jan(1):19-22.
Factors of unspecific defense and immunological state were evaluated in 520 patients with ulcer disease. It was established that these patients revealed disorders of excessive release into the internal medium of the body of food antigens, in particular partially split proteins. The latter induce the immune response. An increase occurs of the production of secretion of IgA in the secretions, IgG in the blood, the T-system of immunity is inhibited, the complement consumption is increased. On the basis of obtained data the author proposes a hypothesis of ulcer formations, the essence of which is that food antigens entering the body causes sensibilization of the organism with a development of an immune-complex reaction of the Arthus phenomenon type in the gastroduodenal zone.
对520例溃疡病患者的非特异性防御因素和免疫状态进行了评估。结果发现，这些患者体内存在食物抗原过度释放到体内介质中的紊乱情况，尤其是部分分解的蛋白质。后者会引发免疫反应。分泌物中IgA的分泌量增加，血液中IgG增加，免疫T系统受到抑制，补体消耗增加。基于所获得的数据，作者提出了溃疡形成的假说，其本质是进入体内的食物抗原会使机体致敏，并在胃十二指肠区域发生阿瑟斯现象型的免疫复合物反应。
