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[基于茶碱试验数据探讨免疫疗法对淋巴瘤T系统的影响]

[The effect of immunotherapy on the T system in lymphoma based on data from the theophylline test].

作者信息

Bratus' G G, Darchuk G F

出版信息

Vrach Delo. 1990 Jan(1):88-90.

PMID:2330723
Abstract

An analysis is presented of the sensitivity of theophyllin test to the level of endogenous modification of E-receptors on T-cells of the peripheral blood and lymph nodes of mice with lymphoma in conditions of immunotherapy with native and Kon A or cholera neuroaminidase treated lymphoma cells. A marked inhibition of the endogenous character of theophyllin-sensitive cells in lymph nodes of mice in all methods of immunotherapy and an increase of the number of theophyllin-resistant cells, more significant in mice immunized with Kon A treated cells.

摘要

本文分析了在使用天然的、经刀豆蛋白A(Kon A)或霍乱神经氨酸酶处理的淋巴瘤细胞进行免疫治疗的条件下,茶碱试验对淋巴瘤小鼠外周血和淋巴结T细胞上E受体内源性修饰水平的敏感性。在所有免疫治疗方法中,小鼠淋巴结中茶碱敏感细胞的内源性特征均受到显著抑制,且茶碱耐药细胞数量增加,在用经Kon A处理的细胞免疫的小鼠中更为明显。

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