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慢性硬膜下血肿的复发可以预测吗?对292例病例的回顾性分析。

Can recurrence of chronic subdural hematoma be predicted? A retrospective analysis of 292 cases.

作者信息

Tugcu Bekir, Tanriverdi Osman, Baydin Serhat, Hergunsel Batu, Günaldı Ömür, Ofluoglu Ender, Alatas Ibrahim, Demirgil Bulent, Emel Erhan

机构信息

Department of Neurosurgery, Bakirkoy Research and Training Hospital for Neurology, Neurosurgery, and Psychiatry, İstanbul, Turkey.

Department of Neurosurgery, Erzurum Research and Training Hospital, Erzurum, Turkey.

出版信息

J Neurol Surg A Cent Eur Neurosurg. 2014 Jan;75(1):37-41. doi: 10.1055/s-0032-1330961. Epub 2013 Jan 10.

Abstract

BACKGROUND

Chronic subdural hematomas are the most common type of intracranial hemorrhage among the elderly. There is a substantial recurrence rate after evacuation by burr-hole surgery. In this study, we aimed to determine the predictors of recurrence after single burr-hole evacuation of chronic subdural hematomas.

METHODS

We retrospectively analyzed 292 consecutive patients with chronic subdural hematoma. Clinical parameters, anamnesis, and previous anticoagulant drug use have been evaluated with univariate and multivariate analyses to determine predictors associated with recurrence.

RESULTS

At least a second surgery was needed in 43 of 292 (14.7%) patients. We showed that recurrence rate was significantly higher in patients with bilateral subdural hematoma, after univariate and multivariate analyses (23.1% versus 11.4%). We did not find any significant relationship between recurrence rate and age, gender, hypertension, and/or diabetes mellitus in anamnesis, preceding head trauma, and time interval between trauma and the operation, previous anticoagulant, and/or antiaggregant therapy.

CONCLUSION

After analysis of all evaluated factors, only bilateral hematoma was found correlated with high recurrence rate (p = 0.01), probably due to previous brain atrophy or existing coagulopathy.

摘要

背景

慢性硬膜下血肿是老年人中最常见的颅内出血类型。钻孔手术清除血肿后复发率较高。在本研究中,我们旨在确定慢性硬膜下血肿单次钻孔清除术后复发的预测因素。

方法

我们回顾性分析了292例连续的慢性硬膜下血肿患者。通过单因素和多因素分析评估临床参数、既往史和既往抗凝药物使用情况,以确定与复发相关的预测因素。

结果

292例患者中有43例(14.7%)至少需要进行二次手术。单因素和多因素分析显示,双侧硬膜下血肿患者的复发率显著更高(23.1%对11.4%)。我们未发现复发率与年龄、性别、高血压和/或糖尿病病史、既往头部外伤、外伤与手术之间的时间间隔、既往抗凝和/或抗血小板治疗之间存在任何显著关系。

结论

在分析所有评估因素后,仅发现双侧血肿与高复发率相关(p = 0.01),可能是由于既往脑萎缩或存在凝血功能障碍。

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