Harran University Medical Faculty, Department of Orthopaedics and Traumatology, Şanlıurfa, Turkey.
Bone Joint J. 2013 Jan;95-B(1):111-4. doi: 10.1302/0301-620X.95B1.29504.
We compared the intracompartmental pressures (ICPs) of open and closed tibial fractures with the same injury pattern in a rabbit model. In all, 20 six-month-old New Zealand White male rabbits were used. They were randomised into two equal groups of ten rabbits; an open fracture group (group 1) and a closed fracture group (group 2). Each anaesthetised rabbit was subjected to a standardised fracture of the proximal half of the right tibia using a custom-made device. In order to create a grade II open fracture in group 1, a 10 mm segment of fascia and periosteum was excised. The ICP in the anterior compartment was monitored at six-hourly intervals for 48 hours. Although there was a statistically significant difference in ICP values within each group (both p < 0.001), there was no significant difference between the groups for all measurements (all p ≥ 0.089). In addition, in both groups there was a statistically significant increase in ICP within the first 24 hours, whereas there was a statistically significant decrease within the second 24 hours (p < 0.001 for both groups). We conclude that open tibial fractures should be monitored for the development of acute compartment syndrome to the same extent as closed fractures.
我们比较了在兔模型中具有相同损伤模式的开放性和闭合性胫骨骨折的间隔内压力（ICPs）。总共使用了 20 只 6 个月大的新西兰白兔。将它们随机分为两组，每组 10 只兔子；开放性骨折组（第 1 组）和闭合性骨折组（第 2 组）。每个麻醉兔子都使用定制设备对右胫骨的近端进行标准化骨折。为了在第 1 组中创建 10 毫米的筋膜和骨膜段的 II 级开放性骨折。在 48 小时内每 6 小时监测前间隔的 ICP。尽管每个组内的 ICP 值都存在统计学上的显著差异（均 p <0.001），但所有测量值在组间均无显著差异（均 p ≥0.089）。此外，两组中 ICP 在最初 24 小时内均呈统计学显著增加，而在第二 24 小时内则呈统计学显著降低（两组均 p <0.001）。我们得出结论，开放性胫骨骨折应与闭合性骨折一样监测急性间隔综合征的发生。
