Traini Tonino, Caputi Sergio, Gherlone Enrico, Degidi Marco, Piattelli Adriano
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti-Pescara, Italy; Department of Dentistry, San Raffaele Hospital, Vita Salute University, Milano, Italy.
Clin Implant Dent Relat Res. 2014 Oct;16(5):718-27. doi: 10.1111/cid.12038. Epub 2013 Jan 11.
The surface chemical and physical properties of materials used for implants have a major influence on blood clot organization. This study aims to evaluate the blood clot extension (bce) on zirconia and titanium. bce was measured in association to surface roughness (Ra) and static contact angle (θ).
Forty disk-shaped samples of sandblasted yttria tetragonal zirconia polycrystal (sb-YTZP), machined titanium (m-Ti), and sandblasted, high-temperature, acid-etched titanium (p-Ti) were used in the present study. About 0.2 mL of human blood, immediately dropped onto the specimen's surface and left in contact for 5 minutes at room temperature, was used to measure the bce. Specimens were observed under confocal scanning laser and scanning electron microscopes.
The bce (mean × 10(7) ± standard deviation [SD] × 10(6) μm(2) ) was 2.97 ± 6.68 for m-Ti, 5.64 ± 6.83 for p-Ti, and 3.61 ± 7.67 for sb-YTZP. p-Ti samples showed a significantly higher bce. Ra (mean ± SD [μm]) was 0.56 ± 0.7 for m-Ti, 3.78 ± 0.8 for p-Ti, and 2.68 ± 0.6 for sb-YTZP. The difference was not significant between sb-YTZP and p-Ti. θ (mean ± SD) was 55.6 ± 5.6 for m-Ti, 48.7 ± 2.8 for sb-YTZP, and 38.0 ± 2.2 for p-Ti. The difference was not significant between m-Ti and sb-YTZP.
The sb-YTZP demonstrated a significantly lesser amount of bce compared with p-Ti specimens, notwithstanding that any significant difference was present between Ra and θ.
用于植入物的材料的表面化学和物理性质对血凝块形成有重大影响。本研究旨在评估氧化锆和钛表面的血凝块扩展情况（bce）。bce的测量与表面粗糙度（Ra）和静态接触角（θ）相关。
本研究使用了40个盘状样本，分别为喷砂处理的钇稳定四方氧化锆多晶体（sb-YTZP）、加工钛（m-Ti）以及喷砂、高温、酸蚀钛（p-Ti）。将约0.2 mL人体血液立即滴在样本表面，并在室温下保持接触5分钟，用于测量bce。样本在共聚焦扫描激光显微镜和扫描电子显微镜下观察。
m-Ti的bce（平均值×10(7) ± 标准差[SD]×10(6) μm(2) ）为2.97 ± 6.68，p-Ti为5.64 ± 6.83，sb-YTZP为3.61 ± 7.67。p-Ti样本的bce显著更高。m-Ti的Ra（平均值±SD [μm]）为0.56 ± 0.7，p-Ti为3.78 ± 0.8，sb-YTZP为2.68 ± 0.6。sb-YTZP和p-Ti之间差异不显著。m-Ti的θ（平均值±SD）为55.6 ± 5.6，sb-YTZP为48.7 ± 2.8，p-Ti为38.0 ± 2.2。m-Ti和sb-YTZP之间差异不显著。
尽管在Ra和θ方面不存在显著差异，但与p-Ti样本相比，sb-YTZP的bce显著较少。
