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心理社会干预减少同时存在酒精和非法药物使用问题的个体的酒精消费:Cochrane 综述。

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users: Cochrane Review.

机构信息

Graduate Entry Medical School, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.

出版信息

Syst Rev. 2013 Jan 12;2:3. doi: 10.1186/2046-4053-2-3.

Abstract

BACKGROUND

Problem alcohol use is common among illicit drug users and is associated with adverse health outcomes. It is also an important factor in poor prognosis among drug users with hepatitis C virus (HCV) as it impacts progression to hepatic cirrhosis or opiate overdose in opioid users. The aim of this systematic review was to assess the effects of psychosocial interventions for problem alcohol use in adult illicit drug users with concurrent problem alcohol use (principally, problem drug users of opiates and stimulants).

METHODS

We searched the following databases (November 2011): Cochrane Library, PUBMED, EMBASE, CINAHL, PsycINFO and reference list of articles. We also searched conference proceedings and online registers of clinical trials. Two reviewers independently assessed risk of bias and extracted data from included randomized controlled trials.

RESULTS

Four studies (594 participants) were included in this review. Half of the trials were rated as having a high or unclear risk of bias. The four studies considered six different psychosocial interventions grouped into four comparisons: 1) cognitive-behavioral coping skills training versus 12-step facilitation (N = 41), 2) brief intervention versus treatment as usual (N = 110), 3) hepatitis health promotion versus motivational interviewing (N = 256), and 4) brief motivational intervention versus assessment-only group (N = 187). Differences between studies precluded any pooling of data. Findings are described for each trial individually. Most findings were not statistically significant except for comparison 2: decreased alcohol use at three months (risk ratio (RR) 0.32; 95% confidence interval (CI) 0.19 to 0.54) and nine months (RR 0.16; 95% CI 0.08 to 0.33) in the treatment-as-usual group and comparison 4: reduced alcohol use in the brief motivational intervention (RR 1.67; 95% CI 1.08 to 2.60).

CONCLUSIONS

No conclusion can be made because of the paucity of the data and the low quality of the retrieved studies.

摘要

背景

问题性酒精使用在非法药物使用者中很常见,并且与不良健康结果相关。它也是丙型肝炎病毒(HCV)药物使用者预后不良的一个重要因素,因为它会影响到阿片类药物使用者的肝纤维化或阿片类药物过量的进展。本系统评价的目的是评估针对同时存在问题性酒精使用的成年非法药物使用者(主要是阿片类药物和兴奋剂的问题药物使用者)的问题性酒精使用的心理社会干预的效果。

方法

我们检索了以下数据库(2011 年 11 月):Cochrane 图书馆、PubMed、EMBASE、CINAHL、PsycINFO 和文章参考文献。我们还检索了会议记录和临床试验在线登记处。两位评审员独立评估了偏倚风险,并从纳入的随机对照试验中提取数据。

结果

本综述纳入了四项研究(594 名参与者)。一半的试验被评为高风险或不确定风险。这四项研究考虑了六种不同的心理社会干预措施,分为四个比较组:1)认知行为应对技能训练与 12 步促进(N=41);2)简短干预与常规治疗(N=110);3)肝炎健康促进与动机性访谈(N=256);4)简短动机性访谈与仅评估组(N=187)。由于研究之间存在差异,无法对数据进行汇总。每个试验的结果都单独描述。除了比较 2:常规治疗组三个月(风险比(RR)0.32;95%置信区间(CI)0.19 至 0.54)和九个月(RR 0.16;95%CI 0.08 至 0.33)的酒精使用减少,以及比较 4:简短动机性干预组的酒精使用减少(RR 1.67;95%CI 1.08 至 2.60)外,大多数结果均无统计学意义。

结论

由于数据的缺乏和检索到的研究质量低,无法得出结论。

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