School of Medicine, University of Sydney, Sydney, New South Wales, Australia.
Rheum Dis Clin North Am. 2013 Feb;39(1):107-22. doi: 10.1016/j.rdc.2012.10.002. Epub 2012 Nov 9.
Although there is an abundance of literature regarding the development of knee osteoarthritis after rupture of the anterior cruciate ligament (ACL), the mechanism underlying this link is not clear. Recent studies have reported that several factors may be predictive of the development of osteoarthritis, including damage to the menisci and articular cartilage during the initial trauma, altered knee biomechanics after injury, and episodic instability. This article summarizes recent developments in the understanding of the joint damage resulting from an ACL tear, and the influence that current and future treatment methods may have on the long-term progression to osteoarthritis.
尽管有大量关于前交叉韧带（ACL）断裂后膝关节骨关节炎发展的文献，但这一关联的机制尚不清楚。最近的研究报告称，有几个因素可能与骨关节炎的发展有关，包括初始创伤时半月板和关节软骨的损伤、损伤后膝关节生物力学的改变以及间歇性不稳定。本文总结了 ACL 撕裂导致的关节损伤的最新研究进展，以及当前和未来的治疗方法可能对长期进展为骨关节炎的影响。
