Department of Physiotherapy, Royal North Shore Hospital, St Leonards, New South Wales 2065, Australia.
Rheum Dis Clin North Am. 2013 Feb;39(1):213-33. doi: 10.1016/j.rdc.2012.11.001. Epub 2012 Nov 26.
International evidence-based guidelines recommend a multitude of nonsurgical treatment options for the management of osteoarthritis. This article summarizes the evidence available for patient characteristics that have been analyzed as potential predictors of response to nonsurgical interventions for patients with hip and knee osteoarthritis. The specific variables targeted for this review include body mass index, psychological factors, muscle strength, tibiofemoral alignment, radiographic changes, and signs of inflammation. Several studies provide moderate to good evidence of potential predictors of response to nonsurgical treatments, and areas for future research are illuminated.
国际循证指南推荐了多种非手术治疗选择来管理骨关节炎。本文总结了可用于分析患者特征的证据,这些特征被分析为髋膝关节骨关节炎患者对非手术干预反应的潜在预测因子。本次综述的具体目标变量包括体重指数、心理因素、肌肉力量、胫股对线、放射影像学改变和炎症迹象。有几项研究提供了对非手术治疗反应的潜在预测因子的中等至良好证据,并阐明了未来研究的方向。