[黏膜保护——一种可评估的价值？大鼠实验研究]
[Mucosa protection--an assessable value? An experimental study in rats].
作者信息
Albrecht R, Nowak W
机构信息
Klinik und Poliklinik für Chirurgie, Medizinischen Akademie Erfurt, DDR.
出版信息
Gastroenterol J. 1990;49(4):168-71.
PMID:2331313
Abstract
Reduced mucosaprotection is a main factor for development of peptic ulcer disease. The quantity is difficult to estimate. We did it by measuring the acid output as the aggressive factor and we sized the resulting mucosalesions. In the gastric corpus we could not find any change in mucosaprotectionindex after cimetidine, pirenzepine and vagotomy. But in the duodenum protection was increased after pirenzepine and vagotomy.
摘要
黏膜保护作用减弱是消化性溃疡疾病发生的一个主要因素。其数量难以估计。我们通过测量作为攻击因素的胃酸分泌量来进行评估，并对由此产生的黏膜损伤进行大小测定。在胃体部，西咪替丁、哌仑西平和迷走神经切断术后，我们未发现黏膜保护指数有任何变化。但在十二指肠，哌仑西平和迷走神经切断术后保护作用增强。
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