甘草酸抑制病毒生长并使病毒颗粒失活。
Glycyrrhizic acid inhibits virus growth and inactivates virus particles.
作者信息
Pompei R, Flore O, Marccialis M A, Pani A, Loddo B
出版信息
Nature. 1979 Oct 25;281(5733):689-90. doi: 10.1038/281689a0.
DOI:10.1038/281689a0
PMID:233133
Abstract
Screening investigations in antiviral action of plant extracts have revealed that a component of Glycyrrhiza glabra roots, found to be glycyrrhizie acid, is active against viruses. We report here that this drug inhibits growth and cytopathology of several unrelated DNA and RNA viruses, while not affecting cell activity and ability to replicate. In addition, glycyrrhizic acid inactivates herpes simplex virus particles irreversibly.
摘要
对植物提取物抗病毒作用的筛选研究表明，光果甘草根中的一种成分（即甘草酸）具有抗病毒活性。我们在此报告，这种药物可抑制几种不相关的DNA和RNA病毒的生长及细胞病变，同时不影响细胞活性和复制能力。此外，甘草酸可使单纯疱疹病毒颗粒不可逆地失活。
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