Plainis Sotiris, Kontadakis George, Feloni Eftychia, Giannakopoulou Trisevgeni, Tsilimbaris Miltiadis K, Pallikaris Ioannis G, Moschandreas Joanna
Institute of Vision and Optics, University of Crete, Greece.
Optom Vis Sci. 2013 Feb;90(2):174-8. doi: 10.1097/OPX.0b013e31827ce251.
To compare visual acuity (VA) assessed in healthy eyes and eyes with diabetic retinopathy (DR) using three different logMAR charts: the Sloan letter European-wide chart, the tumbling E chart, and the Landolt C chart.
Measurements on one eye of 40 volunteers (aged 29 ± 4 years) without visual impairment and 31 DR patients (aged 70 ± 9 years) with mild/moderate visual impairment were included. Visual acuity was assessed, with habitual refractive correction, using each of the three charts. Bland-Altman charts were constructed, and 95% limits of agreement were calculated to measure agreement.
Mean VA in the group of young adults was -0.05 ± 0.10 (Sloan letter), -0.02 ± 0.13 (tumbling E), and 0.00 ± 0.12 (Landolt C) logMAR. Average VA estimates differed to a statistically significant extent between all charts. Mean VA in the DR group was 0.46 ± 0.25 (Sloan letter), 0.48 ± 0.26 (tumbling E), and 0.59 ± 0.28 (Landolt C). A statistically significant difference was observed for average Sloan letter versus Landolt C (p < 0.001) and tumbling E versus Landolt C (p < 0.001) acuities. Moreover, in healthy eyes, a moderate correlation (r = -0.38, p = 0.015) was found between the discrepancy in Sloan letter and Landolt C acuity and the mean VA estimate. The 95% limits of agreement were wide (more than approximately 0.2 logMAR for each comparison) and wider in the DR group chart comparisons than in healthy eyes.
Landolt C charts resulted in worse VA estimates compared with letter and tumbling E charts in both young adults and visually impaired subjects with DR. These differences seem more pronounced in DR patients who exhibit worse VAs. The specific study population must be considered in comparing outcomes from different clinical practices.
使用三种不同的对数最小分辨角视力(logMAR)图表,即斯隆字母全欧洲通用图表、翻转E图表和兰多尔特C图表,比较健康眼睛和患有糖尿病视网膜病变(DR)的眼睛的视力(VA)。
纳入40名无视力损害的志愿者(年龄29±4岁)的一只眼睛以及31名患有轻度/中度视力损害的DR患者(年龄70±9岁)的一只眼睛进行测量。使用三种图表中的每一种,在进行习惯性屈光矫正的情况下评估视力。构建布兰德-奥特曼图表,并计算95%一致性界限以测量一致性。
年轻成年人组的平均视力在斯隆字母图表中为-0.05±0.10 logMAR,在翻转E图表中为-0.02±0.13 logMAR,在兰多尔特C图表中为0.00±0.12 logMAR。所有图表之间的平均视力估计值在统计学上有显著差异。DR组的平均视力在斯隆字母图表中为0.46±0.25 logMAR,在翻转E图表中为0.48±0.26 logMAR,在兰多尔特C图表中为0.59±0.28 logMAR。观察到斯隆字母图表与兰多尔特C图表的平均视力(p < 0.001)以及翻转E图表与兰多尔特C图表的平均视力(p < 0.001)存在统计学显著差异。此外,在健康眼睛中,斯隆字母图表和兰多尔特C图表的视力差异与平均视力估计值之间存在中度相关性(r = -0.38,p = =0.015)。95%一致性界限较宽(每次比较超过约0.2 logMAR),并且在DR组图表比较中比在健康眼睛中更宽。
与字母图表和翻转E图表相比,兰多尔特C图表在年轻成年人以及患有DR的视力受损受试者中导致的视力估计值更差。这些差异在视力较差的DR患者中似乎更为明显。在比较不同临床实践的结果时,必须考虑特定的研究人群。