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Prediction of response to anti-EGFR antibodies in metastatic colorectal cancer: looking beyond EGFR inhibition.

作者信息

Ottaiano Alessandro, Capuozzo Maurizio, Nasti Guglielmo, Maiolino Piera, De Angelis Valentina, Scala Stefania, Iaffaioli Rosario V

机构信息

Department of Colorectal Oncology at the National Cancer Institute, "G. Pascale" foundation, via M. Semmola Naples, Italy.

出版信息

Front Immunol. 2013 Jan 7;3:409. doi: 10.3389/fimmu.2012.00409. eCollection 2012.

Abstract
摘要

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本文引用的文献

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Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
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Combination strategies to enhance antitumor ADCC.
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Clin Cancer Res. 2011 Sep 1;17(17):5668-73. doi: 10.1158/1078-0432.CCR-11-0239. Epub 2011 Jul 25.
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KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.
Lancet Oncol. 2011 Jun;12(6):594-603. doi: 10.1016/S1470-2045(10)70209-6. Epub 2010 Dec 14.
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The evolving role of monoclonal antibodies in colorectal cancer: early presumptions and impact on clinical trial development.
Oncologist. 2010;15(1):73-84. doi: 10.1634/theoncologist.2009-0167. Epub 2010 Jan 12.

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