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赤子爱胜蚓体腔液的抗菌活性:细菌侵染后溶菌酶和蛋白质的转录与翻译调控

Antibacterial activity of Eisenia fetida andrei coelomic fluid: transcription and translation regulation of lysozyme and proteins evidenced after bacterial infestation.

作者信息

Hirigoyenberry F, Lassalle F, Lassegues M

机构信息

Département de Physiologie des Invertébrés, Université de Bordeaux, Talence, France.

出版信息

Comp Biochem Physiol B. 1990;95(1):71-5. doi: 10.1016/0305-0491(90)90250-w.

DOI:10.1016/0305-0491(90)90250-w
PMID:2331874
Abstract
  1. After bacterial infestation lysozyme and antibacterial activities are enhanced, peaking at 4 hr and 3 days, respectively. 2. Both humoral defenses require RNA and protein de novo synthesis in response to pathogenic bacteria injection (actinomycin D and cycloheximide experiments). 3. Antibacterial activity exists naturally at some basic level, involving regular translation of stable RNAs. 4. When antibacterial activity reaches its maximum after bacterial injection, proteins responsible for it undergo a turn-over. 5. Lysozyme and antibacterial proteins cannot account for the whole response to bacterial infestation; some cellular defense mechanisms like phagocytosis are involved at the same time.
摘要
  1. 细菌感染后,溶菌酶和抗菌活性增强,分别在4小时和3天达到峰值。2. 两种体液防御都需要响应致病性细菌注射(放线菌素D和环己酰亚胺实验)从头合成RNA和蛋白质。3. 抗菌活性在一定基础水平上自然存在,涉及稳定RNA的常规翻译。4. 细菌注射后抗菌活性达到最大值时,负责该活性的蛋白质会更新。5. 溶菌酶和抗菌蛋白不能解释对细菌感染的整个反应;同时还涉及一些细胞防御机制,如吞噬作用。

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Antibacterial activity of Eisenia fetida andrei coelomic fluid: transcription and translation regulation of lysozyme and proteins evidenced after bacterial infestation.赤子爱胜蚓体腔液的抗菌活性:细菌侵染后溶菌酶和蛋白质的转录与翻译调控
Comp Biochem Physiol B. 1990;95(1):71-5. doi: 10.1016/0305-0491(90)90250-w.
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Antibacterial activity of Eisenia fetida andrei coelomic fluid: III--Relationship within the polymorphic hemolysins.赤子爱胜蚓体腔液的抗菌活性:III - 多态溶血素之间的关系。
Dev Comp Immunol. 1991 Winter;15(1-2):27-32. doi: 10.1016/0145-305x(91)90044-y.
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Protein analysis of earthworm coelomic fluid. III. Isolation and characterization of several bacteriostatic molecules from Eisenia fetida andrei.蚯蚓体腔液的蛋白质分析。III. 从安德爱胜蚓中分离和鉴定几种抑菌分子。
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Cellular but not humoral antibacterial activity of earthworms is inhibited by Aroclor 1254.阿罗氯丹1254可抑制蚯蚓的细胞抗菌活性,但不抑制其体液抗菌活性。
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PCBs increase molecular-related activities (lysozyme, antibacterial, hemolysis, proteases) but inhibit macrophage-related functions (phagocytosis, wound healing) in earthworms.
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Effect of experimental microbial challenge on the expression of defense molecules in Eisenia foetida earthworm.实验性微生物攻击对赤子爱胜蚓防御分子表达的影响。
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Microbial environment affects innate immunity in two closely related earthworm species Eisenia andrei and Eisenia fetida.微生物环境影响两种亲缘关系密切的蚯蚓物种——安德爱胜蚓和赤子爱胜蚓的先天免疫。
PLoS One. 2013 Nov 1;8(11):e79257. doi: 10.1371/journal.pone.0079257. eCollection 2013.
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Protein analysis of earthworm coelomic fluid: 1) polymorphic system of the natural hemolysin of Eisenia fetida andrei.蚯蚓体腔液的蛋白质分析:1)安德爱胜蚓天然溶血素的多态系统。
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Correlation between the activity of digestive enzymes and nonself recognition in the gut of Eisenia andrei earthworms.在赤子爱胜蚓肠道中,消化酶的活性与非自身识别之间的关系。
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