中国东部地区志贺菌分离株的抗生素耐药性和整合子分子特征。
High prevalence of antibiotic resistance and molecular characterization of integrons among Shigella isolates in Eastern China.
机构信息
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
出版信息
Antimicrob Agents Chemother. 2013 Mar;57(3):1549-51. doi: 10.1128/AAC.02102-12. Epub 2013 Jan 14.
Abstract
A total of 747 Shigella isolates were collected from hospitals in Jiangsu Province of China. Susceptibilities to antimicrobials and integrons were tested. A total of 78.3% of S. flexneri isolates and a total of 74.3% S. sonei isolates were resistant to at least three antibiotics. Of the Shigella isolates, 74.7% had integron I and 82.6% had integron II. The conjunction of the high prevalence of integrons in Shigella and high resistance to antimicrobials will lead to rapid dissemination of resistant genes in this region.
摘要
共从中国江苏省的医院收集了 747 株志贺氏菌分离株。对其进行了药敏试验和整合子检测。78.3%的福氏志贺菌分离株和 74.3%的宋内志贺菌分离株至少对三种抗生素耐药。在志贺氏菌分离株中，74.7%有整合子 I，82.6%有整合子 II。志贺氏菌中整合子的高流行率和对抗生素的高度耐药性将导致该地区耐药基因的快速传播。
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