Habe Koji, Wada Hideo, Ito-Habe Naomi, Suzuki Hikoji, Nobori Tsutomu, Mizutani Hitoshi
Department of Dermatology, Mie University Graduate School of Medicine, Japan.
Intern Med. 2013;52(2):269-72. doi: 10.2169/internalmedicine.52.8308. Epub 2013 Jan 15.
One hundred and eleven patients with antiphospholipid antibodies (aPL) were diagnosed at Mie University Hospital during the past 17 years. Two of these patients developed disseminated intravascular coagulation (DIC). The first patient twice developed DIC complicated by pancreatitis and pregnancy, while in the second case, no specific causative complications for DIC were identified. The details of these cases imply that aPL is associated with DIC and/or is a potent triggering factor for DIC.
在过去17年中，三重大学医院诊断出111例抗磷脂抗体（aPL）患者。其中两名患者发生了弥散性血管内凝血（DIC）。首例患者两次发生DIC，并伴有胰腺炎和妊娠，而第二例患者未发现导致DIC的特定并发症。这些病例的详细情况表明，aPL与DIC有关，和/或aPL是DIC的一个强效触发因素。
