Kobayashi Takao
Hamamatsu Medical Center, Shizuoka, Japan.
J Obstet Gynaecol Res. 2014 Jun;40(6):1500-6. doi: 10.1111/jog.12426.
Obstetrical disseminated intravascular coagulation (DIC) is usually a very acute, serious complication of pregnancy. The obstetrical DIC score helps with making a prompt diagnosis and starting treatment early. This DIC score, in which higher scores are given for clinical parameters rather than for laboratory parameters, has three components: (i) the underlying diseases; (ii) the clinical symptoms; and (iii) the laboratory findings (coagulation tests). It is justifiably appropriate to initiate therapy for DIC when the obstetrical DIC score reaches 8 points or more before obtaining the results of coagulation tests. Improvement of blood coagulation tests and clinical symptoms are essential to the efficacy evaluation for treatment after a diagnosis of obstetrical DIC. Therefore, the efficacy evaluation criteria for obstetrical DIC are also defined to enable follow-up of the clinical efficacy of DIC therapy.
产科弥散性血管内凝血(DIC)通常是一种非常急性、严重的妊娠并发症。产科DIC评分有助于快速诊断并尽早开始治疗。该DIC评分针对临床参数而非实验室参数给出更高分数,它有三个组成部分:(i)基础疾病;(ii)临床症状;(iii)实验室检查结果(凝血试验)。在获得凝血试验结果之前,当产科DIC评分达到8分或更高时启动DIC治疗是合理的。凝血试验和临床症状的改善对于产科DIC诊断后的治疗疗效评估至关重要。因此,还定义了产科DIC的疗效评估标准,以便对DIC治疗的临床疗效进行随访。