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[Long-term remission after nonmyeloablative allogeneic bone marrow transplantation in a relapsed Hodgkin lymphoma patient with CNS involvement].

作者信息

Shimura Hanae, Imai Yoichi, Ishiyama Midori, Yoshinaga Kentaro, Shiseki Masayuki, Mori Naoki, Teramura Masanao, Motoji Toshiko

机构信息

Department of Hematology, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

Rinsho Ketsueki. 2012 Dec;53(12):1991-6.

Abstract

Intracranial involvement of relapsed Hodgkin lymphoma (HL) is quite rare and its prognosis is very poor. We report a patient with relapsed HL with central nervous system (CNS) involvement after autologous stem cell transplantation successfully treated with allogeneic bone marrow transplantation with reduced intensity conditioning regimen. A standard therapy for relapsed CNS HL has not yet established. To the best of our knowledge, this is the first case report describing allogeneic stem cell transplantation for relapsed CNS HL in an elderly patient. Our results in this case suggest that allogeneic stem cell transplantation could be a useful therapeutic option in relapsed CNS HL patients, if their CNS lesions are controlled before stem cell transplantation.

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