Shimura Hanae, Imai Yoichi, Ishiyama Midori, Yoshinaga Kentaro, Shiseki Masayuki, Mori Naoki, Teramura Masanao, Motoji Toshiko
Department of Hematology, Tokyo Women's Medical University, Tokyo, Japan.
Rinsho Ketsueki. 2012 Dec;53(12):1991-6.
Intracranial involvement of relapsed Hodgkin lymphoma (HL) is quite rare and its prognosis is very poor. We report a patient with relapsed HL with central nervous system (CNS) involvement after autologous stem cell transplantation successfully treated with allogeneic bone marrow transplantation with reduced intensity conditioning regimen. A standard therapy for relapsed CNS HL has not yet established. To the best of our knowledge, this is the first case report describing allogeneic stem cell transplantation for relapsed CNS HL in an elderly patient. Our results in this case suggest that allogeneic stem cell transplantation could be a useful therapeutic option in relapsed CNS HL patients, if their CNS lesions are controlled before stem cell transplantation.