沙特门诊新兴炎症性肠病：693 例报告。

Emerging inflammatory bowel disease in saudi outpatients: a report of 693 cases.

机构信息

Gastroenterology Unit, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Saudi J Gastroenterol. 2013 Jan-Feb;19(1):16-22. doi: 10.4103/1319-3767.105915.

BACKGROUND/AIM: Inflammatory bowel disease (IBD) is a chronic disease of unknown etiology and considered traditionally as a disease of the western world. Recently, rising trends have been observed in countries previously known to have a low prevalence and incidence. The aim of this study is to collect epidemiological data on IBD outpatients and to add data from the Kingdom of Saudi Arabia (KSA) to the available IBD literature.

PATIENTS AND METHODS

The medical records of 693 Saudi patients with IBD over a period of 17 years, between 1993 and 2009, were reviewed. The demographic and clinical data and methods of diagnosis were retrieved.

RESULTS

The total number of patients in this cohort was 693. It constituted 238 (34.3%) ulcerative colitis (UC) and 455 (65.7%) Crohn's disease (CD) patients. UC was steady throughout the years, whereas only 1.2 CD patients were diagnosed per year in the first 11 years, and 73.7 per year in the last six years. The median age of UC patients was 34 years, ranging from 10 to 80 years with a peak between 21 and 40 years and in CD it was 27 years, ranging from 11 to 73 years with a peak between 11 and 30 years. There was a male preponderance of 1.5:1 and 2:1, respectively. The rest of the data is discussed in this study.

CONCLUSION

IBD is no longer a rare disease in KSA. UC is in a steady state, whereas CD is increasing significantly and far outnumbering UC.

背景/目的：炎症性肠病（IBD）是一种病因不明的慢性疾病，传统上被认为是一种西方疾病。最近，在以前发病率和患病率较低的国家，发病率呈上升趋势。本研究的目的是收集 IBD 门诊患者的流行病学数据，并将来自沙特阿拉伯王国（KSA）的数据添加到现有的 IBD 文献中。

患者和方法

回顾了 1993 年至 2009 年间 17 年间 693 例沙特 IBD 患者的病历。检索了人口统计学和临床数据以及诊断方法。

结果

本队列的患者总数为 693 例。其中溃疡性结肠炎（UC）患者 238 例（34.3%），克罗恩病（CD）患者 455 例（65.7%）。UC 患者人数一直保持稳定，而在前 11 年，每年仅诊断出 1.2 例 CD 患者，而在最后 6 年中，每年诊断出 73.7 例。UC 患者的中位年龄为 34 岁，范围为 10-80 岁，高峰年龄在 21-40 岁之间；CD 患者的中位年龄为 27 岁，范围为 11-73 岁，高峰年龄在 11-30 岁之间。男性患病率分别为 1.5:1 和 2:1。其余数据在本研究中进行了讨论。