McGowan M P, Pratter M R, Nash G
Department of Medicine, University of Massachusetts School of Medicine, Worcester.
Chest. 1990 May;97(5):1258-9. doi: 10.1378/chest.97.5.1258.
We report a case in which ARDS was the presenting manifestation of testicular choriocarcinoma with numerous metastases to the lungs. We also review the literature on other cases in which ARDS developed as a result of neoplastic infiltration of the lungs and stress the fact that it may be indistinguishable from ARDS from other causes. Because potentially effective chemotherapy for the neoplastic processes most commonly involved (ie, germ cell tumors, acute leukemia and lymphoma) is available, we emphasize the importance of considering a neoplastic disorder in the differential diagnosis of cases of otherwise unexplained ARDS. Early accurate diagnosis could conceivably result in an improved outcome in these cases.
我们报告了一例以急性呼吸窘迫综合征（ARDS）为首发表现的睾丸绒毛膜癌，且伴有肺内多发转移。我们还回顾了有关因肺部肿瘤浸润而发生ARDS的其他病例的文献，并强调其可能与其他原因导致的ARDS难以区分这一事实。鉴于针对最常见的肿瘤性疾病（即生殖细胞肿瘤、急性白血病和淋巴瘤）有潜在有效的化疗方法，我们强调在鉴别诊断不明原因的ARDS病例时考虑肿瘤性疾病的重要性。可以想象，早期准确诊断可能会改善这些病例的预后。
