[海南冬青的化学成分]

[Chemical constituents from Ilex hainanensis].

作者信息

Peng Bo, Huang Wei-Hua, Zhao Jing, Liu Hua-Gang

机构信息

State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.

出版信息

Zhong Yao Cai. 2012 Aug;35(8):1251-4.

PMID:23320356

Abstract

OBJECTIVE

To investigate the chemical constituents from Ilex hainanensis.

METHODS

The compounds were isolated and purified by various chromatographic techniques. The structures were identified by mass and NMR spectral data.

RESULTS

Ten compounds were isolated and identified as Ilexgenin A (1), 3beta, 19alpha-dihydroxyolean-12-ene-24,28-Dioicacid-28-O-beta-D-glucopyranoside (2), Ilexsaponin A1 (3), 2-(Caffeoyloxy) methyl-3-hydroxy-1-butane-4-O-beta-D-glucopyranoside (4), Dibutyl phthalate (5), Rutin (6), Eriodictyol-7-O-beta-D-glucopyranoside (7), Syringaresinol-4-O-beta-D-glucopyranoside (8), (2E) -2-methyl-2-butene-1, 4-diol-4-O-beta-D-(6"-O- caffeoyl) -glucopyranoside (9), 1-O-caffeoyl-(2E) -2-methyl-2-butene-1, 4-diol-4-O-beta-D- glucopyranoside (10), respectively.

CONCLUSION

Compound 4, 7 - 10 are obtained from this plant for the first time.

摘要

目的

研究海南冬青的化学成分。

方法

采用多种色谱技术对化合物进行分离纯化，并通过质谱和核磁共振光谱数据鉴定其结构。

结果

分离鉴定出10个化合物，分别为冬青皂苷元A（1）、3β,19α - 二羟基齐墩果 - 12 - 烯 - 24,28 - 二酸 - 28 - O - β - D - 吡喃葡萄糖苷（2）、冬青皂苷A1（3）、2 - （咖啡酰氧基）甲基 - 3 - 羟基 - 1 - 丁烷 - 4 - O - β - D - 吡喃葡萄糖苷（4）、邻苯二甲酸二丁酯（5）、芦丁（6）、圣草酚 - 7 - O - β - D - 吡喃葡萄糖苷（7）、丁香树脂醇 - 4 - O - β - D - 吡喃葡萄糖苷（8）、（2E） - 2 - 甲基 - 2 - 丁烯 - 1,4 - 二醇 - 4 - O - β - D - （6″ - O - 咖啡酰基） - 吡喃葡萄糖苷（9）、1 - O - 咖啡酰基 - （2E） - 2 - 甲基 - 2 - 丁烯 - 1,4 - 二醇 - 4 - O - β - D - 吡喃葡萄糖苷（10）。