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机器人胃切除术治疗大型胃肠道间质瘤。

Robotic gastric resection of large gastrointestinal stromal tumors.

机构信息

Department of Digestive Surgery and Liver Unit, St. Maria Hospital, Terni, Italy.

出版信息

Int J Surg. 2013;11(2):191-6. doi: 10.1016/j.ijsu.2013.01.002. Epub 2013 Jan 12.

Abstract

BACKGROUND

The stomach is the most common site for gastrointestinal stromal tumors (GIST) development. Surgical treatment consists of excision of the entire neoplastic mass, with sufficient surgical margins within healthy tissue. This can be achieved with different techniques ranging from wedge resections, typical gastric resections, right up to total gastrectomy. There aren't clear guidelines for the use of minimally invasive approach.

MATERIALS AND METHODS

From January 2011 to April 2012, 5 patients with presumed preoperative diagnosis of GIST were treated by robotic surgery at the Unit of Surgery and Advanced Oncologic Therapies, Forlì Hospital, Forlì, Italy. We report operative techniques, perioperative outcomes and follow-up.

RESULTS

Lesions were localized at anterior wall of gastric antrum (N = 2) and near pyloric area (N = 3). Mean tumor size was 5 cm (range 4-7 cm). Surgical procedures were 5 distal gastrectomy. None intervention was converted to open surgery and there weren't major intraoperative complications. Median operative time was 240 min (range 210-300 min) and mean intraoperative blood loss was 96 ml (80-120 ml). All lesions had microscopically negative resection margins. Median follow-up was 13.5 months (range 12-15 months) with a disease-free survival rate of 100%.

CONCLUSIONS

Surgical robotic approach for large GISTs is feasibility and new evidences are needed to clarify the effective role of different surgical strategies.

摘要

背景

胃是胃肠道间质瘤(GIST)发展最常见的部位。手术治疗包括切除整个肿瘤组织,并在健康组织内留有足够的手术切缘。这可以通过不同的技术来实现,从楔形切除术、典型的胃切除术,直到全胃切除术。对于微创方法的使用,目前还没有明确的指南。

材料和方法

从 2011 年 1 月至 2012 年 4 月,意大利福里医院外科和高级肿瘤治疗科对 5 例术前诊断为 GIST 的患者进行了机器人手术治疗。我们报告手术技术、围手术期结果和随访情况。

结果

病变位于胃窦前壁(N=2)和幽门附近(N=3)。平均肿瘤大小为 5cm(范围 4-7cm)。手术方式为 5 例远端胃切除术。无中转开腹,无术中重大并发症。中位手术时间为 240 分钟(范围 210-300 分钟),术中平均出血量为 96ml(80-120ml)。所有病变均有显微镜下阴性切缘。中位随访时间为 13.5 个月(范围 12-15 个月),无病生存率为 100%。

结论

机器人手术方法治疗大型 GIST 是可行的,需要新的证据来阐明不同手术策略的有效作用。

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