Koh Ye-Xin, Goh Brian K P
Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
Duke NUS Medical School, Singapore, Singapore.
Transl Gastroenterol Hepatol. 2017 Dec 12;2:108. doi: 10.21037/tgh.2017.11.20. eCollection 2017.
Minimally invasive surgery has been increasingly performed for gastric gastrointestinal stromal tumors (GIST). In this review we discuss and summarize the current evidence on minimally invasive surgery for gastric GISTs. Laparoscopic resection for gastric GIST has been consistently shown to be associated with superior perioperative outcomes with no compromise in oncological outcomes when compared to open resection in numerous retrospective case-control studies. It has also been shown to be safe and feasible for large tumors or tumors located in unfavorable sites. However, to date, there remains a lack of level 1 evidence from prospective randomized control trials in support of laparoscopic resection.
微创手术已越来越多地应用于胃胃肠道间质瘤（GIST）的治疗。在本综述中，我们讨论并总结了目前关于胃GIST微创手术的证据。在众多回顾性病例对照研究中，与开放手术相比，腹腔镜切除胃GIST一直被证明围手术期效果更佳，且肿瘤学结局不受影响。对于大肿瘤或位于不利部位的肿瘤，腹腔镜切除也已证明是安全可行的。然而，迄今为止，仍缺乏来自前瞻性随机对照试验的一级证据支持腹腔镜切除。
