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[褐煤粉尘对支气管肺系统和免疫活性器官的生物学效应(实验形态学研究)]

[Biological effect of brown coal dust on the bronchopulmonary system and immunocompetent organs (experimental morphological study)].

作者信息

Ivanova L G

出版信息

Gig Tr Prof Zabol. 1990(2):21-4.

PMID:2332183
Abstract

Inhalation of the brown coal samples caused anthracosis with progressive growth in the postinhalation period and concomitant catarrhal-desquamative bronchitis, lymphoid tissue hyperplasia, emphysema, along with granuloma formation. The cases studied were marked with increased number and thickness of the argyrophile and reticuline fibres around the bronchi, vessels, granuloma and in the interalveolar septum. Changes were detected in the immunocompetent organs' state which might influence the homeostasis and the immune system. Complex cytomorphological investigation of the bronchopulmonary and immunocompetent systems can be applied to in biological studies of different aerosols.

摘要

吸入褐煤样本会导致煤尘肺,在吸入后阶段病情会逐渐发展,并伴有卡他性-脱屑性支气管炎、淋巴组织增生、肺气肿以及肉芽肿形成。所研究的病例显示,支气管、血管、肉芽肿周围以及肺泡间隔中的嗜银纤维和网状纤维数量增加且厚度增大。免疫活性器官的状态发生了变化,这可能会影响体内平衡和免疫系统。支气管肺和免疫活性系统的复杂细胞形态学研究可应用于不同气溶胶的生物学研究。

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