Clinical Research & Drug Development Specialist; PATH; New Delhi, India.
Hum Vaccin Immunother. 2013 Apr;9(4):928-31. doi: 10.4161/hv.23514. Epub 2013 Jan 15.
Vaccines have had a major role in enhancing the quality of life and increasing life expectancy. Despite these successes and the development of new vaccine technologies, there remain multiple infectious diseases including AIDS, malaria and tuberculosis that require effective prophylactic vaccines. New and traditional technologies have a role in the development and delivery of the new vaccine candidates. The scientific challenges, opportunities and funding models for developing vaccines for low resource settings are highlighted here.
疫苗在提高生活质量和延长预期寿命方面发挥了重要作用。尽管取得了这些成功,并开发了新的疫苗技术,但仍有多种传染病,包括艾滋病、疟疾和结核病,需要有效的预防性疫苗。新的和传统的技术在开发和提供新的疫苗候选物方面都发挥了作用。本文重点介绍了为资源匮乏环境开发疫苗所面临的科学挑战、机遇和资金模式。