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新兴市场中的新型疫苗开发所面临的科学挑战和机遇：新兴市场中的新技术，2012 年 10 月 16 日-18 日，世界疫苗大会，里昂。

Scientific challenges and opportunities in developing novel vaccines for the emerging and developing markets: New Technologies in Emerging Markets, October 16th-18th 2012, World Vaccine Congress, Lyon.

机构信息

Clinical Research & Drug Development Specialist; PATH; New Delhi, India.

出版信息

Hum Vaccin Immunother. 2013 Apr;9(4):928-31. doi: 10.4161/hv.23514. Epub 2013 Jan 15.

DOI:10.4161/hv.23514
PMID:23322007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3903916/
Abstract

Vaccines have had a major role in enhancing the quality of life and increasing life expectancy. Despite these successes and the development of new vaccine technologies, there remain multiple infectious diseases including AIDS, malaria and tuberculosis that require effective prophylactic vaccines. New and traditional technologies have a role in the development and delivery of the new vaccine candidates. The scientific challenges, opportunities and funding models for developing vaccines for low resource settings are highlighted here.

摘要

疫苗在提高生活质量和延长预期寿命方面发挥了重要作用。尽管取得了这些成功，并开发了新的疫苗技术，但仍有多种传染病，包括艾滋病、疟疾和结核病，需要有效的预防性疫苗。新的和传统的技术在开发和提供新的疫苗候选物方面都发挥了作用。本文重点介绍了为资源匮乏环境开发疫苗所面临的科学挑战、机遇和资金模式。

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Transdermal immunization: biological framework and translational perspectives.经皮免疫接种：生物学框架与转化视角。
Expert Opin Drug Deliv. 2013 Feb;10(2):183-200. doi: 10.1517/17425247.2013.746660. Epub 2012 Dec 21.
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