VA National Serious Mental Illness Treatment Resource and Evaluation Center and VA Health Services Research & Development, , Ann Arbor, Michigan, USA.
Inj Prev. 2013 Oct;19(5):326-30. doi: 10.1136/injuryprev-2012-040631. Epub 2013 Jan 15.
The intent of a death from overdose can be difficult to determine. The goal of this study was to examine the association of psychiatric diagnoses among overdose deaths ruled by a medical examiner as intentional, unintentional and indeterminate intent.
All Veterans Health Administration patients in Fiscal Year 1999 (n=3 291 891) were followed through Fiscal Year 2006. We tested the relative strength of association between psychiatric disorders among types of overdoses (categorised by intent) using multinomial models, adjusted for age, sex, Veterans Affairs priority status and Charlson comorbidity scores. Data were from National Death Index records and patient medical records.
Substance use disorders (SUD) had a stronger association with indeterminate intent overdoses than intentional overdoses (adjusted OR (AOR)=1.80, 95% CI 1.47 to 2.22). SUDs also had a stronger association with unintentional overdoses than intentional (AOR=1.48, 95% CI 1.27 to 1.72), but the reverse was true for all other psychiatric disorders (except post-traumatic stress disorder).
Overdoses ruled indeterminate may be misclassified suicide deaths and are important to suicide surveillance and prevention efforts. Additionally, overdose deaths not classified as suicides may include some cases due to suicidal-like thinking without overt suicidal intent.
药物过量致死的意图可能难以确定。本研究的目的是检验在被法医判定为故意、非故意和不确定意图的药物过量死亡中,精神科诊断与药物过量之间的关联。
在 1999 财政年度(n=3 291 891),对所有退伍军人健康管理局患者进行了随访,随访时间至 2006 财政年度。我们使用多项模型检验了各种药物过量(按意图分类)类型之间的精神障碍之间的关联强度,调整了年龄、性别、退伍军人事务优先级和 Charlson 合并症评分。数据来自国家死亡指数记录和患者病历。
物质使用障碍(SUD)与不确定意图的药物过量比故意药物过量的关联更强(调整后的比值比(AOR)=1.80,95%可信区间 1.47 至 2.22)。SUD 与非故意药物过量的关联也比故意药物过量更强(AOR=1.48,95%可信区间 1.27 至 1.72),但其他所有精神障碍的情况则相反(除创伤后应激障碍)。
判定为不确定意图的药物过量可能被错误地归类为自杀死亡,这对于自杀监测和预防工作很重要。此外,未被归类为自杀的药物过量死亡可能包括一些由于自杀样思维而没有明显自杀意图的病例。