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The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease.

作者信息

Vij Neeraj, Downey Gregory P

出版信息

Am J Respir Crit Care Med. 2013 Jan 15;187(2):120-2. doi: 10.1164/rccm.201211-2011ED.

DOI:10.1164/rccm.201211-2011ED
PMID:23322792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3570650/
Abstract
摘要

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本文引用的文献

1
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.中性粒细胞弹性蛋白酶通过钙蛋白酶降解囊性纤维化跨膜电导调节因子，并在体外和体内使通道功能失活。
Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6.
2
Absence of the cystic fibrosis transmembrane regulator (Cftr) from myeloid-derived cells slows resolution of inflammation and infection.髓系来源细胞中囊性纤维化跨膜转导调节因子（Cftr）的缺失会减缓炎症和感染的消退。
J Leukoc Biol. 2012 Nov;92(5):1111-22. doi: 10.1189/jlb.0412188. Epub 2012 Aug 2.
3
A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease.吸烟相关肺部疾病中获得性囊性纤维化跨膜电导调节因子功能障碍的药物治疗方法。
PLoS One. 2012;7(6):e39809. doi: 10.1371/journal.pone.0039809. Epub 2012 Jun 29.
4
Protease signalling: the cutting edge.蛋白酶信号：前沿领域。
EMBO J. 2012 Apr 4;31(7):1630-43. doi: 10.1038/emboj.2012.42. Epub 2012 Feb 24.
5
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration.香烟烟雾暴露可诱导 CFTR 内化和不溶性，导致气道表面液体脱水。
FASEB J. 2012 Feb;26(2):533-45. doi: 10.1096/fj.11-192377. Epub 2011 Oct 11.
6
The cell biology of phagocytosis.吞噬作用的细胞生物学。
Annu Rev Pathol. 2012;7:61-98. doi: 10.1146/annurev-pathol-011811-132445. Epub 2011 Sep 9.
7
A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system.一种劫持宿主泛素蛋白酶系统的铜绿假单胞菌毒素。
PLoS Pathog. 2011 Mar;7(3):e1001325. doi: 10.1371/journal.ppat.1001325. Epub 2011 Mar 24.
8
Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury.CFTR 依赖性脂筏在香烟烟雾诱导的肺上皮细胞损伤中的关键作用。
Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L811-20. doi: 10.1152/ajplung.00408.2010. Epub 2011 Mar 4.
9
Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema.在肺损伤和肺气肿中，膜囊性纤维化跨膜电导调节剂依赖性神经酰胺信号的关键修饰作用。
J Immunol. 2011 Jan 1;186(1):602-13. doi: 10.4049/jimmunol.1002850. Epub 2010 Dec 6.
10
Lack of cystic fibrosis transmembrane conductance regulator in CD3+ lymphocytes leads to aberrant cytokine secretion and hyperinflammatory adaptive immune responses.CD3+ 淋巴细胞中囊性纤维化跨膜电导调节因子的缺失导致细胞因子分泌异常和过度炎症性适应性免疫反应。
Am J Respir Cell Mol Biol. 2011 Jun;44(6):922-9. doi: 10.1165/rcmb.2010-0224OC. Epub 2010 Aug 19.