The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease.
作者信息
Vij Neeraj, Downey Gregory P
出版信息
Am J Respir Crit Care Med. 2013 Jan 15;187(2):120-2. doi: 10.1164/rccm.201211-2011ED.
Abstract
摘要
相似文献
1
The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease.囊性纤维化跨膜传导调节因子功能的阴阳学说：对慢性肺病的启示
Am J Respir Crit Care Med. 2013 Jan 15;187(2):120-2. doi: 10.1164/rccm.201211-2011ED.
2
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.中性粒细胞弹性蛋白酶通过钙蛋白酶降解囊性纤维化跨膜电导调节因子，并在体外和体内使通道功能失活。
Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6.
3
How do cystic fibrosis transmembrane conductance regulator mutations produce lung disease?囊性纤维化跨膜传导调节因子突变如何导致肺部疾病？
Curr Opin Pulm Med. 1995 Nov;1(6):435-43. doi: 10.1097/00063198-199511000-00002.
4
Novel, mechanism-based therapies for cystic fibrosis.针对囊性纤维化的新型、基于机制的疗法。
Curr Opin Pediatr. 2005 Jun;17(3):385-92. doi: 10.1097/01.mop.0000158846.95469.6f.
5
Yet another role for the cystic fibrosis transmembrane conductance regulator.
Am J Respir Cell Mol Biol. 2000 Jan;22(1):11-4. doi: 10.1165/ajrcmb.22.1.f177.
6
Cystic Fibrosis Transmembrane Conductance Regulator Function in Airway Smooth Muscle. A Novel Role in Cystic Fibrosis Airway Obstruction.囊性纤维化跨膜传导调节因子在气道平滑肌中的功能。在囊性纤维化气道阻塞中的新作用。
Am J Respir Crit Care Med. 2016 Feb 15;193(4):352-3. doi: 10.1164/rccm.201510-2088ED.
7
Structure and function of the cystic fibrosis transmembrane conductance regulator.囊性纤维化跨膜传导调节因子的结构与功能
Braz J Med Biol Res. 1999 Aug;32(8):1021-8. doi: 10.1590/S0100-879X1999000800013.
8
The biogenesis, traffic, and function of the cystic fibrosis transmembrane conductance regulator.囊性纤维化跨膜传导调节因子的生物发生、运输及功能
Int Rev Cytol. 1997;172:193-241. doi: 10.1016/s0074-7696(08)62361-x.
9
Mucin overproduction in chronic inflammatory lung disease.慢性炎症性肺病中的粘蛋白过度产生。
Can Respir J. 2006 Sep;13(6):327-35. doi: 10.1155/2006/901417.
10
Correlating Cystic Fibrosis Transmembrane Conductance Regulator Function with Clinical Features to Inform Precision Treatment of Cystic Fibrosis.将囊性纤维化跨膜电导调节剂功能与临床特征相关联，以指导囊性纤维化的精准治疗。
Am J Respir Crit Care Med. 2019 May 1;199(9):1116-1126. doi: 10.1164/rccm.201901-0145OC.
引用本文的文献
1
Neutrophilic inflammation in bronchiectasis.支气管扩张症中的中性粒细胞性炎症。
Eur Respir Rev. 2025 Apr 2;34(176). doi: 10.1183/16000617.0179-2024. Print 2025 Apr.
2
Inhibition of histone-deacetylase activity rescues inflammatory cystic fibrosis lung disease by modulating innate and adaptive immune responses.组蛋白去乙酰化酶活性的抑制通过调节先天和适应性免疫反应来挽救炎症性囊性纤维化肺病。
Respir Res. 2018 Jan 4;19(1):2. doi: 10.1186/s12931-017-0705-8.
3
Airway Exposure to E-Cigarette Vapors Impairs Autophagy and Induces Aggresome Formation.气道暴露于电子烟蒸汽会损害自噬并诱导聚集体形成。
Antioxid Redox Signal. 2016 Feb 1;24(4):186-204. doi: 10.1089/ars.2015.6367. Epub 2015 Oct 27.
4
Second-hand cigarette smoke impairs bacterial phagocytosis in macrophages by modulating CFTR dependent lipid-rafts.二手烟通过调节囊性纤维化跨膜传导调节因子（CFTR）依赖的脂筏来损害巨噬细胞中的细菌吞噬作用。
PLoS One. 2015 Mar 20;10(3):e0121200. doi: 10.1371/journal.pone.0121200. eCollection 2015.
5
A new method to improve the clinical evaluation of cystic fibrosis patients by mucus viscoelastic properties.一种通过黏液黏弹性特性改善囊性纤维化患者临床评估的新方法。
PLoS One. 2014 Jan 3;9(1):e82297. doi: 10.1371/journal.pone.0082297. eCollection 2014.
本文引用的文献
1
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.中性粒细胞弹性蛋白酶通过钙蛋白酶降解囊性纤维化跨膜电导调节因子，并在体外和体内使通道功能失活。
Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6.
2
Absence of the cystic fibrosis transmembrane regulator (Cftr) from myeloid-derived cells slows resolution of inflammation and infection.髓系来源细胞中囊性纤维化跨膜转导调节因子（Cftr）的缺失会减缓炎症和感染的消退。
J Leukoc Biol. 2012 Nov;92(5):1111-22. doi: 10.1189/jlb.0412188. Epub 2012 Aug 2.
3
A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease.吸烟相关肺部疾病中获得性囊性纤维化跨膜电导调节因子功能障碍的药物治疗方法。
PLoS One. 2012;7(6):e39809. doi: 10.1371/journal.pone.0039809. Epub 2012 Jun 29.
4
Protease signalling: the cutting edge.蛋白酶信号：前沿领域。
EMBO J. 2012 Apr 4;31(7):1630-43. doi: 10.1038/emboj.2012.42. Epub 2012 Feb 24.
5
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration.香烟烟雾暴露可诱导 CFTR 内化和不溶性，导致气道表面液体脱水。
FASEB J. 2012 Feb;26(2):533-45. doi: 10.1096/fj.11-192377. Epub 2011 Oct 11.
6
The cell biology of phagocytosis.吞噬作用的细胞生物学。
Annu Rev Pathol. 2012;7:61-98. doi: 10.1146/annurev-pathol-011811-132445. Epub 2011 Sep 9.
7
A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system.一种劫持宿主泛素蛋白酶系统的铜绿假单胞菌毒素。
PLoS Pathog. 2011 Mar;7(3):e1001325. doi: 10.1371/journal.ppat.1001325. Epub 2011 Mar 24.
8
Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury.CFTR 依赖性脂筏在香烟烟雾诱导的肺上皮细胞损伤中的关键作用。
Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L811-20. doi: 10.1152/ajplung.00408.2010. Epub 2011 Mar 4.
9
Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema.在肺损伤和肺气肿中，膜囊性纤维化跨膜电导调节剂依赖性神经酰胺信号的关键修饰作用。
J Immunol. 2011 Jan 1;186(1):602-13. doi: 10.4049/jimmunol.1002850. Epub 2010 Dec 6.
10
Lack of cystic fibrosis transmembrane conductance regulator in CD3+ lymphocytes leads to aberrant cytokine secretion and hyperinflammatory adaptive immune responses.CD3+ 淋巴细胞中囊性纤维化跨膜电导调节因子的缺失导致细胞因子分泌异常和过度炎症性适应性免疫反应。
Am J Respir Cell Mol Biol. 2011 Jun;44(6):922-9. doi: 10.1165/rcmb.2010-0224OC. Epub 2010 Aug 19.
Zotero 插件