Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Occup Environ Med. 2013 Jun;70(6):402-7. doi: 10.1136/oemed-2012-100889. Epub 2013 Jan 15.
Although a study among utility workers found an increased risk for acute myocardial infarction and arrhythmia-related deaths associated with occupational extremely low-frequency magnetic fields (ELF-MF) exposure, later studies largely failed to replicate these findings. This study investigated the association between occupational ELF-MF exposure and cardiovascular disease (CVD) mortality within a community-based prospective cohort study.
The Netherlands Cohort Study is a prospective cohort study among 120 852 men and women aged 55-69 years at baseline. Participants were followed-up for CVD mortality over a period of 10 years, resulting in 8200 CVD deaths. Information on occupational history and potential confounders, such as educational level, smoking and alcohol use were collected at baseline through a self-administered questionnaire. Occupational ELF-MF exposure was assigned using a job-exposure matrix. Associations with CVD mortality were analysed using Cox regression.
Ever low or high exposure to ELF-MF showed no association with total CVD mortality (HR of 1.02, 95% CI 0.99 to 1.06), nor with any cause-specific subtypes of CVD mortality. Other ELF-MF exposure metrics showed no increased risks either.
In this study, we found no indication of an association between occupational ELF-MF exposure and risk of CVD mortality.
尽管一项针对公用事业工人的研究发现，与职业极低频磁场（ELF-MF）暴露相关的急性心肌梗死和心律失常相关死亡风险增加，但后来的研究在很大程度上未能复制这些发现。本研究在一项基于社区的前瞻性队列研究中调查了职业 ELF-MF 暴露与心血管疾病（CVD）死亡率之间的关联。
荷兰队列研究是一项针对 120852 名年龄在 55-69 岁基线时的男性和女性的前瞻性队列研究。参与者在 10 年内接受了 CVD 死亡率的随访，导致 8200 例 CVD 死亡。基线时通过自我管理问卷收集了职业史和潜在混杂因素（如教育程度、吸烟和饮酒）的信息。职业 ELF-MF 暴露使用工作暴露矩阵进行分配。使用 Cox 回归分析与 CVD 死亡率的关联。
长期低或高暴露于 ELF-MF 与总 CVD 死亡率（HR 为 1.02，95%CI 0.99 至 1.06）或任何特定原因的 CVD 死亡率均无关联。其他 ELF-MF 暴露指标也没有显示出增加的风险。
在这项研究中，我们没有发现职业 ELF-MF 暴露与 CVD 死亡率风险之间存在关联的迹象。
