Ocul Immunol Inflamm. 2013;21(1):84-6. doi: 10.3109/09273948.2012.734537.
Immunoglobulin G (IgG) subclass deficiency is a rare primary immunodeficiency syndrome characterized by recurrent infections and autoimmune disorders. However, there have been no reports of ocular involvement, either inflammatory or infectious, in association with IgG subclass deficiency. The authors report the first case of retinal vasculitis that led to the diagnosis of IgG subclass deficiency, in a patient with a history of inflammatory bowel disease and recurrent infections of previously unknown origin.
免疫球蛋白 G（IgG）亚类缺陷是一种罕见的原发性免疫缺陷综合征，其特征是反复感染和自身免疫性疾病。然而，目前尚无 IgG 亚类缺陷与眼部炎症或感染有关的报道。作者报告了首例因视网膜血管炎而诊断为 IgG 亚类缺陷的病例，该患者有炎症性肠病病史和先前不明原因的反复感染。
