Güneşer S, Antmen B, Altintaş D, Yilmaz M
Department of Pediatrics, Cukurova University Faculty of Medicine, Adana.
Turk J Pediatr. 1996 Apr-Jun;38(2):161-8.
We studied the frequency of IgG subclass deficiency in 61 children (ages 1-7 years, mean 3.8 years) with recurrent respiratory tract infections by using the radial immunodiffusion method. The overall frequency of IgG subclass deficiency was found to be 39.3 percent (24 patients). Among 26 children who had major immunoglobulin abnormalities, we found IgG subclass deficiency in 11 patients (42.3%). In children with normal immunoglobulin levels, the frequency of IgG subclass deficiency was 37.1 percent (13 patients).
我们采用放射免疫扩散法研究了61例（年龄1至7岁，平均3.8岁）反复呼吸道感染儿童的IgG亚类缺陷发生率。发现IgG亚类缺陷的总体发生率为39.3%（24例患者）。在26例有主要免疫球蛋白异常的儿童中，我们发现11例患者存在IgG亚类缺陷（42.3%）。在免疫球蛋白水平正常的儿童中，IgG亚类缺陷的发生率为37.1%（13例患者）。
