Department of Community Health & Psychiatry, University of the West Indies, Mona, Jamaica.
Psychol Health Med. 2013;18(4):451-60. doi: 10.1080/13548506.2012.749353. Epub 2013 Jan 16.
This study explored how locus of control (LOC), depression and quality of life (QOL) interplay in patients with sickle cell disease. One hundred and forty-three sickle cell clinic patients with consecutive clinic consultations completed the Multidimensional Health Locus of Control and Short Factor 36 (SF-36) scales as well as the Beck Depression Inventory. Participants in this study had higher scores on the "chance", "other people" and "internal" domains of LOC than persons with a number of other chronic illnesses in a previous study. Hierarchical regression analyses showed that high scores on the "internal" domain of LOC were associated with better QOL and fewer symptoms of depression. Depressive symptoms were greater in persons with high scores on the "other people" LOC domain and in younger persons. These findings would suggest that it is possible that interventions which enhance internal LOC and discourage "other people" orientations might improve QOL and ameliorate depression among persons with sickle cell disease.
这项研究探讨了控制源（LOC）、抑郁和生活质量（QOL）在镰状细胞病患者中的相互作用。143 名镰状细胞诊所患者在连续的诊所就诊中完成了多维健康控制源量表和简短 36 项健康状况调查问卷（SF-36）以及贝克抑郁量表。与之前一项研究中患有许多其他慢性疾病的人相比，本研究的参与者在 LOC 的“机会”、“他人”和“内部”领域的得分更高。层次回归分析表明，LOC 的“内部”领域得分高与更好的 QOL 和更少的抑郁症状有关。在 LOC 得分高的“他人”领域和年轻人中，抑郁症状更严重。这些发现表明，增强内部 LOC 和抑制“他人”取向的干预措施可能会提高镰状细胞病患者的生活质量并改善抑郁症状。
