Department of Infectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark.
Euro Surveill. 2013 Jan 10;18(2):20350.
Denmark faced an outbreak of verocytotoxin-producing E. coli (VTEC) O157:H7 infections in autumn 2012. Thirteen cases were diagnosed of which eight had haemolytic uraemic syndrome (HUS). Epidemiological investigations suggested ground beef as the vehicle of the outbreak. The outbreak strain had a rare toxin gene subtype profile: eae, vtx1a and vtx2a, and a high proportion of HUS (62%) among cases, a finding previously linked with the outbreak subtype profile. Toxin subtyping can be useful to identify high risk VTEC strains.
2012 年秋，丹麦爆发了产志贺毒素大肠埃希菌（VTEC）O157：H7 感染疫情。确诊了 13 例病例，其中 8 例患有溶血尿毒综合征（HUS）。流行病学调查表明，汉堡牛肉饼是此次疫情的传播媒介。疫情菌株具有罕见的毒素基因亚型谱：eae、vtx1a 和 vtx2a，且病例中 HUS 的比例较高（62%），这一发现与以往疫情的亚型谱有关。毒素亚型分析有助于识别高危产志贺毒素大肠埃希菌菌株。
