Gorokhov A S, Shipulin V M, Podoksenov Iu K, Kozlov B N, Kuznetsov M S, Shishneva E V, Panfilov D S, Plotnikov M P, Lebedeva E V
Angiol Sosud Khir. 2012;18(4):100-5.
The present work was aimed at assessing safety and efficacy of hypoxic preconditioning of the brain as a method of protecting the central nervous system during operations on the internal carotid artery in patients presenting with atherosclerotic lesions of the carotid arteries. The study included a total of 72 patients who underwent carotid endarterectomy for haemodynamically significant atherosclerosis of carotid arteries. Based on the obtained findings, a conclusion was made on a possibility of using intraoperative hypoxic preconditioning for prevention of ischaemic complications from the development in the perioperative period.
本研究旨在评估脑缺氧预处理作为一种在患有颈动脉粥样硬化病变的患者进行颈内动脉手术期间保护中枢神经系统的方法的安全性和有效性。该研究共纳入72例因颈动脉血流动力学显著粥样硬化而接受颈动脉内膜切除术的患者。基于所得结果,得出了关于术中使用缺氧预处理预防围手术期发生缺血性并发症可能性的结论。