Faculty of Biosciences and Bioengineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia.
Appl Microbiol Biotechnol. 2013 Feb;97(4):1475-88. doi: 10.1007/s00253-012-4663-2. Epub 2013 Jan 17.
The Bacillaceae family members are a good source of bacteria for bioprocessing and biotransformation involving whole cells or enzymes. In contrast to Bacillus and Geobacillus, Anoxybacillus is a relatively new genus that was proposed in the year 2000. Because these bacteria are alkali-tolerant thermophiles, they are suitable for many industrial applications. More than a decade after the first report of Anoxybacillus, knowledge accumulated from fundamental and applied studies suggests that this genus can serve as a good alternative in many applications related to starch and lignocellulosic biomasses, environmental waste treatment, enzyme technology, and possibly bioenergy production. This current review provides the first summary of past and recent discoveries regarding the isolation of Anoxybacillus, its medium requirements, its proteins that have been characterized and cloned, bioremediation applications, metabolic studies, and genomic analysis. Comparisons to some other members of Bacillaceae and possible future applications of Anoxybacillus are also discussed.
芽孢杆菌科成员是涉及全细胞或酶的生物加工和生物转化的细菌的良好来源。与芽孢杆菌和地芽孢杆菌相比，耐冷芽孢杆菌是一个相对较新的属，于 2000 年提出。由于这些细菌是耐碱嗜热菌，因此它们适用于许多工业应用。在首次报道耐冷芽孢杆菌十多年后，从基础和应用研究中积累的知识表明，该属在与淀粉和木质纤维素生物质、环境废物处理、酶技术以及可能的生物能源生产相关的许多应用中可以作为一个很好的替代选择。本综述提供了过去和最近关于耐冷芽孢杆菌的分离、其培养基要求、已鉴定和克隆的蛋白质、生物修复应用、代谢研究和基因组分析的发现的首次总结。还讨论了与芽孢杆菌科的其他一些成员的比较以及耐冷芽孢杆菌的可能未来应用。
