Rezai Mohammad-Reza, Cowan Brett R, Sherratt Neal, Finn Joseph D, Wu Frederick C W, Cruickshank J Kennedy
Cardiovascular Research Group, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Blood Press Monit. 2013 Apr;18(2):111-8. doi: 10.1097/MBP.0b013e32835d3663.
Simple reproducible methods of measuring arterial stiffness, a powerful index of prognosis, are becoming available.
To compare the pulse wave transit time (TT) and pulse wave velocity (PWV) between MRI and an arm cuff-based oscillometric method, the Arteriograph.
MRI phase-contrast data were acquired at the aortic arch and just above the aortic bifurcation in 49 men (age 53±6 years). Supine left-arm Arteriograph measurements were made after MRI using the surface sternal notch to symphysis pubis pathway length.
MRI TT and PWV covered 86% of aortic root-bifurcation length omitting a mean 4.7 cm of proximal ascending aorta. Arteriograph TT (71±9 ms) was 6.6 ms [95% confidence interval (CI) 3.9-9.4] or 10% higher than MRI (64±10 ms). Arteriograph PWV (7.9±1.3 m/s) was 1.33 m/s (95% CI 0.95-1.70) higher than MRI (6.6±1.2 m/s), primarily because the surface aortic length was 70 mm (95% CI 59-81) longer than MRI. Arteriograph-MRI PWV difference decreased to 0.31 m/s (95% CI 0.01-0.61) when Arteriograph PWV was calculated using the MRI aortic path length and to 0.25 m/s (95% CI -0.05 to 0.55) after correcting for the aortic segments omitted in the MRI method. After similar TT corrections for MRI, the Arteriograph-MRI difference in TT reduced to 3.2 ms (95% CI 0.2-6).
TT estimations by Arteriograph and MRI are close. More accurate length estimation from MRI-derived models improves Arteriograph PWV measurement.
测量动脉僵硬度（一种强大的预后指标）的简单可重复方法已逐渐可用。
比较磁共振成像（MRI）与基于手臂袖带的示波法（动脉造影仪）之间的脉搏波传播时间（TT）和脉搏波速度（PWV）。
对49名男性（年龄53±6岁）在主动脉弓和主动脉分叉上方进行MRI相位对比数据采集。MRI检查后，使用胸骨上切迹至耻骨联合的体表路径长度，对仰卧位左臂进行动脉造影仪测量。
MRI的TT和PWV覆盖了主动脉根部至分叉长度的86%，近端升主动脉平均遗漏4.7厘米。动脉造影仪的TT（71±9毫秒）比MRI（64±10毫秒）高6.6毫秒[95%置信区间（CI）3.9 - 9.4]，即高10%。动脉造影仪的PWV（7.9±1.3米/秒）比MRI（6.6±1.2米/秒）高1.33米/秒（95% CI 0.95 - 1.70），主要是因为体表主动脉长度比MRI长70毫米（95% CI 59 - 81）。当使用MRI主动脉路径长度计算动脉造影仪PWV时，动脉造影仪与MRI的PWV差值降至0.31米/秒（95% CI 0.01 - 0.61），在对MRI方法中遗漏的主动脉节段进行校正后，差值降至0.25米/秒（95% CI -0.05至0.55）。对MRI进行类似的TT校正后，动脉造影仪与MRI的TT差值降至3.2毫秒（95% CI 0.2 - 6）。
动脉造影仪和MRI对TT的估计相近。基于MRI模型进行更准确的长度估计可改善动脉造影仪对PWV的测量。
