在 Gen-Probe Panther 仪器上，用于检测共生奈瑟氏菌物种和淋病奈瑟氏球菌的 APTIMA Combo 2 和 APTIMA GC 检测方法的分析特异性和灵敏度。
Analytical specificity and sensitivity of the APTIMA Combo 2 and APTIMA GC assays for detection of commensal Neisseria species and Neisseria gonorrhoeae on the Gen-Probe Panther instrument.
机构信息
WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for Pathogenic Neisseria, Örebro, Sweden.
出版信息
Sex Transm Dis. 2013 Feb;40(2):175-8. doi: 10.1097/OLQ.0b013e3182787e45.
PMID:23324980
Abstract
Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 isolates of nongonococcal Neisseria and related species and 205 gonococcal isolates.
摘要
淋病奈瑟菌的基因检测正在取代培养以提高诊断灵敏度。一些核酸扩增检测的特异性并不理想。在此，当对 298 株非淋球菌奈瑟菌和相关物种以及 205 株淋病奈瑟菌分离株进行确认性检测时，Gen-Probe APTIMA Combo 2 和 APTIMA GC 检测法的特异性和敏感性均为 100%。
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