Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Chemistry. 2013 Feb 25;19(9):3125-30. doi: 10.1002/chem.201204056. Epub 2013 Jan 16.
A new functional-group tolerant, rhodium-catalyzed, sulfide-reduction process is combined with rhodium-catalyzed chelation-controlled hydroacylation reactions to give a traceless hydroacylation protocol. Aryl- and alkenyl aldehydes can be combined with both alkenes, alkynes and allenes to give traceless products in high yields. A preliminary mechanistic proposal is also presented.
一种新的功能基团耐受性、铑催化、硫化物还原工艺与铑催化螯合控制氢甲酰化反应相结合，形成了一种无痕迹氢甲酰化反应方案。芳基和烯基醛可以与烯烃、炔烃和丙二烯结合，以高产率得到无痕迹产物。还提出了初步的机理建议。
