Wands K, Merskey H, Hachinski V C, Fisman M, Fox H, Boniferro M
Department of Research, London Psychiatric Hospital, Ontario, Canada.
J Am Geriatr Soc. 1990 May;38(5):535-8. doi: 10.1111/j.1532-5415.1990.tb02404.x.
We report findings on a study of anxiety and depression by questionnaire in 50 patients with mild dementia and 134 control subjects using the Hospital Anxiety and Depression Scale. Thirty-eight percent of patients and 9% of controls had a possible or probable diagnosis of an anxiety disorder. Possible or probable depression was found in 28% of the patients and 3% of the controls. These rates for the patients were above those in normal populations. All patients and control subjects were tested with the Extended Scale for Dementia (ESD). Neither group showed a significant relationship between depression and ESD scores. In the control subjects there was a negative correlation (P less than .006) between anxiety and cognitive scores, one that was not found in the patients.
我们报告了一项针对50名轻度痴呆患者和134名对照受试者,使用医院焦虑抑郁量表通过问卷调查对焦虑和抑郁进行研究的结果。38%的患者和9%的对照受试者可能或很可能被诊断为焦虑症。28%的患者和3%的对照受试者被发现可能或很可能患有抑郁症。患者的这些比率高于正常人群。所有患者和对照受试者都接受了扩展痴呆量表(ESD)测试。两组中抑郁与ESD评分之间均未显示出显著关系。在对照受试者中,焦虑与认知评分之间存在负相关(P小于0.006),而在患者中未发现这种相关性。