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在罕见的伴有关节外强直的烟雾病病例中,对髋关节异位骨化进行手术切除。

Surgical excision of heterotopic ossification of hip in a rare case of Moyamoya disease with extra articular ankylosis.

作者信息

Palanisami Dhanasekararaja, Shanmuganathan Rajasekaran, Jeyaraman Arun

机构信息

Department of Orthopaedic Surgery, Ganga Medical Centre and Hospital, Coimbatore, Tamil Nadu, India.

出版信息

Indian J Orthop. 2012 Nov;46(6):714-7. doi: 10.4103/0019-5413.104238.

DOI:10.4103/0019-5413.104238
PMID:23325979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3543894/
Abstract

We report a case of isolated ossification of iliopsoas with ankylosis of the left hip in a 27-year-old female. The patient was diagnosed to have Moyamoya disease, a rare chronic occlusive disorder of cerebrovascular circulation following an acute onset of hemiplegia. The patient presented 9 months later to us with ankylosis of left hip which was successfully treated by surgical excision of the heterotopic bone and there was no recurrence at the end of 5 years. A review of literature failed to reveal a similar case with isolated and complete ossification of iliopsoas muscle associated with Moyamoya disease which required surgical intervention. Surgical excision resulted in dramatic improvement in the quality of life. Surgical excision of neurogenic type of heterotopic ossification is a very successful procedure and timely intervention after maturity of mass is very important to prevent the onset of secondary complications and to avoid recurrence.

摘要

我们报告一例27岁女性,患有孤立性髂腰肌骨化并伴有左髋关节强直。该患者被诊断为烟雾病,这是一种罕见的慢性脑血管循环闭塞性疾病,急性起病后出现偏瘫。9个月后,患者因左髋关节强直前来就诊,通过手术切除异位骨成功治愈,5年末未见复发。文献回顾未发现与烟雾病相关的孤立性、完全性髂腰肌骨化且需要手术干预的类似病例。手术切除显著改善了生活质量。神经源性异位骨化的手术切除是一种非常成功的手术,肿块成熟后及时干预对于预防继发并发症的发生和避免复发非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/7740acff8885/IJOrtho-46-714-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/7c660f7f7090/IJOrtho-46-714-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/60a8da78d616/IJOrtho-46-714-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/7740acff8885/IJOrtho-46-714-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/7c660f7f7090/IJOrtho-46-714-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/60a8da78d616/IJOrtho-46-714-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d303/3543894/7740acff8885/IJOrtho-46-714-g003.jpg

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本文引用的文献

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Matrix metalloproteinase-9 is a diagnostic marker of heterotopic ossification in a murine model.基质金属蛋白酶-9 是一种在鼠模型中异位骨化的诊断标志物。
Tissue Eng Part A. 2011 Oct;17(19-20):2487-96. doi: 10.1089/ten.TEA.2011.0007. Epub 2011 Aug 2.
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Orthopedics. 2011 Mar 11;34(3):177. doi: 10.3928/01477447-20110124-08.
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Moyamoya disease: recent progress and outlook.烟雾病:最新进展与展望
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Radiation therapy for preventing recurrence of neurogenic heterotopic ossification.预防神经源性异位骨化复发的放射治疗。
Orthopedics. 2009 Sep;32(9). doi: 10.3928/01477447-20090728-33.
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Moyamoya disease and moyamoya syndrome.烟雾病和烟雾综合征。
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Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).进行性骨化性纤维发育不良(FOP)患者结缔组织祖细胞的骨形态发生蛋白(BMP)信号失调及成骨分化增强。
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The prophylaxis and treatment of heterotopic ossification following lower limb arthroplasty.下肢关节置换术后异位骨化的预防与治疗。
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