Center of AIDS Treatment with Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, 16 Dongzhimennei South Street, Dongcheng District, Beijing 100700, China.
Evid Based Complement Alternat Med. 2012;2012:950757. doi: 10.1155/2012/950757. Epub 2012 Dec 27.
To assess the effects of TCHM on patients with HIV infection and AIDS, we reviewed eleven randomized placebo-controlled trials involving 998 patients. Due to the limited number of RCTs for included trials and the small sample size of each study, we are not able to draw firm conclusions concerning TCHM therapy in treating patients with HIV infection and AIDS. However, some high-quality clinical studies do exist. Studies of diarrhea and oral candidiasis, which are challenging symptoms of AIDS, were demonstrated to have positive effects. Study of peripheral leukocytes, which are a side effect of antiretroviral drugs, suggested that an integrated treatment approach may be of benefit. The overall methodological quality of the trials was adequate; however, randomization methods should be clearly described and fully reported in these trials according to the Consolidated Standards of Reporting Trials (CONSORT).
为了评估中药（TCHM）对 HIV 感染者和艾滋病患者的影响，我们回顾了 11 项随机安慰剂对照试验，共纳入 998 名患者。由于纳入研究的 RCT 数量有限，且每项研究的样本量均较小，因此我们尚无法就 TCHM 治疗 HIV 感染者和艾滋病患者得出确切结论。然而，确有一些高质量的临床研究存在。对于艾滋病具有挑战性的腹泻和口腔念珠菌病的研究表明其具有积极作用。对于外周白细胞的研究提示，综合治疗方法可能有益。这些试验的整体方法学质量是足够的；但是，根据《CONSORT 报告标准》，这些试验应明确描述并充分报告随机分组方法。
