Rich Zachary Clarke, Liu Chuncheng, Ma Qingyan, Hu Fengyu, Cai Weiping, Tang Xiaoping, Tucker Joseph David
UNC-Project China, Number 2 Lujing Road, Guangzhou, 510095, China.
Center for Medical Anthropology and Behavioral Health, School of Sociology and Anthropology, Sun Yat-Sen University, Guangzhou, China.
Asian Pac J Trop Dis. 2015 Sep;5(9):687-690. doi: 10.1016/S2222-1808(15)60913-6. Epub 2015 Aug 14.
There are over 100 clinical trials worldwide focused on developing an HIV cure. Research participants will assume substantial individual risks while receiving little or no individual benefit. Physicians will have important dual roles of leading HIV cure research studies and guiding patient expectations. Many low and middle-income nations have started HIV cure trials, including China. The goal of this study was to better understand physician attitudes, behaviors, and perceptions of HIV cure research within the context of China. We conducted a quantitative and qualitative evidence review of published literature on physician perceptions of HIV cure in China. Quantitative survey data revealed that physicians rarely believed HIV was curable, but this perception may be more common compared to other countries. Qualitative data showed that inconsistent terminology used among physicians may contribute to the perception of HIV as curable. The belief that HIV is curable among some physicians in China may be related to the influence of traditional Chinese medicine beliefs. Rather than seeking elimination of pathogens, traditional Chinese medicine aims to achieve harmony between organs and a vital life force. In this context, HIV infection can be seen as a temporary state of imbalance rather than an irreversible change. There is a wide range of physician perceptions about HIV cure in China. Conflicting information about HIV cure from physicians and other sources could thwart the progress of HIV cure research. Enhancing patient-physician communication about ongoing HIV cure research trials will be important for developing an HIV cure.
全球有100多项临床试验致力于研发治愈艾滋病病毒（HIV）的方法。研究参与者在接受治疗时将承担巨大的个人风险，却很少或几乎无法获得个人益处。医生将扮演重要的双重角色，既要领导HIV治愈研究，又要引导患者的期望。许多低收入和中等收入国家，包括中国，已经开始了HIV治愈试验。本研究的目的是在中国的背景下，更好地了解医生对HIV治愈研究的态度、行为和看法。我们对已发表的关于中国医生对HIV治愈看法的文献进行了定量和定性的证据综述。定量调查数据显示，医生很少相信HIV是可以治愈的，但与其他国家相比，这种看法可能更为普遍。定性数据表明，医生之间使用的术语不一致可能导致认为HIV可治愈的看法。中国一些医生认为HIV可治愈的观点可能与中医观念的影响有关。中医的目标不是消除病原体，而是实现器官与生命力之间的和谐。在这种背景下，HIV感染可被视为一种暂时的失衡状态，而非不可逆转的变化。中国医生对HIV治愈的看法存在很大差异。医生和其他来源关于HIV治愈的相互矛盾的信息可能会阻碍HIV治愈研究的进展。加强患者与医生之间关于正在进行的HIV治愈研究试验的沟通，对于研发HIV治愈方法至关重要。
