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阿米巴肝脓肿患者的血清免疫球蛋白和补体

Serum immunoglobulins and complement in patients suffering from amoebic liver abscess.

作者信息

Ahmed L

机构信息

Department of Tropical Medicine, Faculty of Medicine, Cairo University, Egypt.

出版信息

J Egypt Soc Parasitol. 1990 Jun;20(1):23-8.

PMID:2332650
Abstract

Immunoglobulins IgG, IgM & IgA and complement C3 were studied in 24 patients suffering from amoebic liver abscesses (ALA) before and two months after therapy. The results were compared with those of 12 healthy controls. IgG and IgA showed significant higher level in ALA patients than the normal controls, P less than 0.001 and P less than 0.01 respectively. IgM level was also higher than the normal controls but the difference was insignificant. Follow up of these Igs showed marked drop two months after therapy. C3 level was found statistically higher in ALA before therapy than that of the normal controls and that of patients two months after therapy. Correlation between C3 level and the size of the abscess showed that its level was statistically higher in large abscesses P less than 0.05.

摘要

对24例阿米巴肝脓肿(ALA)患者在治疗前及治疗后两个月进行了免疫球蛋白IgG、IgM和IgA以及补体C3的研究。将结果与12名健康对照者的结果进行比较。IgG和IgA在ALA患者中的水平显著高于正常对照者,P分别小于0.001和P小于0.01。IgM水平也高于正常对照者,但差异不显著。对这些免疫球蛋白的随访显示,治疗后两个月显著下降。发现治疗前ALA患者的C3水平在统计学上高于正常对照者以及治疗后两个月患者的C3水平。C3水平与脓肿大小之间的相关性表明,在大脓肿中其水平在统计学上更高,P小于0.05。

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