Abdel-Ghaffar F, Bashtar A R, el-Toukhy A
Faculty of Science, Cairo University, Egypt.
J Egypt Soc Parasitol. 1990 Jun;20(1):281-7.
The endogenous stages of Eimeria arvicanthi were studied after experimental infection with pure strain in the rat Arvicanthis n. niloticus. The prepatent period was 5 days, while the patent period extended to the 11th day p.i. Two asexual generations were determined in the epithelial cells of the upper part of the colon, while the sexual one was found in the crypts of Lieberkühn. Schizonts of the 1st generation were found 60 hrs p.i., measuring 9 X 4 microns and contained 4-8 merozoites, however those of the 2nd generation were found at 96 hrs p.i., measured 14 X 10 microns and contained 8-12 merozoites. Gamonts were firstly recorded at 108 hrs p.i., after growth they differentiated and gave rise to gametes. Macrogametes were 19 X 17 microns with large nuclei and wall-forming bodies in their cytoplasm. Microgamonts (14 X 11 microns) were irregular in shape and after many nuclear divisions produce many microgametes. Eimeria arvicanthi was pathogenic and about 60% of the experimentally infected rats with 3-5 X 10(5) sporulated oocysts were died till the 9th day p.i.
在用纯菌株对尼罗多乳鼠进行实验性感染后，对阿氏艾美耳球虫的内源性阶段进行了研究。潜隐期为5天，而感染后第11天仍处于发病期。在结肠上部的上皮细胞中确定有两个无性繁殖世代，而有性繁殖世代则在利伯库恩隐窝中发现。感染后60小时发现第一代裂殖体，大小为9×4微米，含4 - 8个裂殖子，而第二代裂殖体在感染后96小时发现，大小为14×10微米，含8 - 12个裂殖子。配子体在感染后108小时首次记录到，生长后分化产生配子。大配子大小为19×17微米，有大细胞核，细胞质中有成壁体。小配子体（14×11微米）形状不规则，经过多次核分裂产生许多小配子。阿氏艾美耳球虫具有致病性，用3 - 5×10⁵个孢子化卵囊对实验感染的大鼠进行感染，约60%的大鼠在感染后第9天死亡。
